479950
Aldolase Antibody 38C2, murine catalytic monoclonal antibody
average Mw ~150,000, powder (Lyophilized, contains pbs)
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About This Item
MDL number:
UNSPSC Code:
12352200
Recommended Products
antibody product type
primary antibodies
form
powder (Lyophilized, contains pbs)
mol wt
average Mw ~150,000
storage temp.
−20°C
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Application
Biocatalyst for aldol condensations, especially for the si-facial addition of aliphatic ketones to aldehydes. Antibody 38C2 catalyzes aldol, crossed aldol, retro aldol, decarboxylation of β-keto acids, self aldol, and Robinson annulations. The biocatalyst can accept a variety of substrates with different physico-chemical properties.
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Kit Components Only
Product No.
Description
- 10 mg
- 5-6.5 mg
- antibody 10 mg
- phosphate buffer salts 5-6.5 mg
Certificates of Analysis (COA)
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R A Lerner et al.
Science (New York, N.Y.), 252(5006), 659-667 (1991-05-03)
Immunochemistry has historically focused on the nature of antigenicity and antibody-antigen recognition. However, in the last 5 years, the field of immunochemistry has taken a new direction. With the aid of mechanistic and synthetic chemistry, the vast network of molecules
P Wirsching et al.
Science (New York, N.Y.), 270(5243), 1775-1782 (1995-12-15)
For almost 200 years inert antigens have been used for initiating the process of immunization. A procedure is now described in which the antigen used is so highly reactive that a chemical reaction occurs in the antibody combining site during
J Wagner et al.
Science (New York, N.Y.), 270(5243), 1797-1800 (1995-12-15)
Antibodies that catalyze the aldol reaction, a basic carbon-carbon bond-forming reaction, have been generated. The mechanism for antibody catalysis of this reaction mimics that used by natural class I aldolase enzymes. Immunization with a reactive compound covalently trapped a Lys
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