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347957

Sigma-Aldrich

Glycine tert-butyl ester hydrochloride

97%, for peptide synthesis

Synonym(s):

tert-Butyl aminoacetate hydrochloride

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About This Item

Linear Formula:
H2NCH2CO2C(CH3)3 · HCl
CAS Number:
27532-96-3
Molecular Weight:
167.63
Beilstein:
3989048
MDL number:
MFCD00058255
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24861538
NACRES:
NA.22

product name

Glycine tert-butyl ester hydrochloride, 97%

Assay

97%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

mp

141-143 °C (lit.)

application(s)

peptide synthesis

SMILES string

Cl.CC(C)(C)OC(=O)CN

InChI

1S/C6H13NO2.ClH/c1-6(2,3)9-5(8)4-7;/h4,7H2,1-3H3;1H

InChI key

OSWULUXZFOQIRU-UHFFFAOYSA-N

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Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Arzneimittel-Forschung, 34(6), 687-690 (1984-01-01)
The synergistic amplification of the anticonvulsant effects of direct and indirect GABA agonists by glycine has previously been demonstrated. We show in the present report that the anticonvulsant effect of vinyl GABA, a GABA-T (4-aminobutyrate: 2-oxoglutarate aminotransferase) inhibitor with antiepileptic
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Cross-linked polystyrene-bound and poly(ethylene glycol)-bound phase-transfer catalysts as well as homopolymers of cinchona alkaloid derivatives have been synthesised. Both soluble and insoluble polymers have been investigated. The enantioselective alkylation of N-diphenyl methylene glycine t-butyl ester has been successfully carried out
Ming-Qing Hua et al.
Chemical communications (Cambridge, England), 47(5), 1631-1633 (2010-12-01)
An efficient, catalytic, diastereo- and enantioselective conjugate addition of N-(diphenylmethylene)glycine tert-butyl ester to β-aryl substituted enones was realized in the presence of 1 mol% of newly desired dinuclear N-spiro-ammonium salts, affording functionalized α-amino acid derivatives in 57-98% yields with high
V De Filippis et al.
Biochemistry, 37(39), 13507-13515 (1998-09-30)
Hirudin is the most potent and specific inhibitor of thrombin, a key enzyme in the coagulation process existing in equilibrium between its procoagulant (fast) and anticoagulant (slow) form. In a previous study, we described the solid-phase synthesis of a Trp3
M Nakoji et al.
Organic letters, 3(21), 3329-3331 (2001-10-12)
[reaction: see text]. A chiral phase-transfer catalyst has been applied to the asymmetric allylation of the tert-butyl glycinate-benzophenone Schiff base with various allylic acetates for the first time to give the allylated products in good yields and with comparable to
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