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219746

Sigma-Aldrich

DL-Homocysteic acid

97%

Synonym(s):

DL-2-Amino-4-sulfobutyric acid

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About This Item

Linear Formula:
HO3SCH2CH2CH(NH2)CO2H
CAS Number:
504-33-6
Molecular Weight:
183.18
EC Number:
207-991-0
MDL number:
MFCD00007536
UNSPSC Code:
12352100
PubChem Substance ID:
24853141
NACRES:
NA.22

Assay

97%

form

solid

mp

273 °C (dec.) (lit.)

solubility

water: soluble 50 mg/mL, clear to slightly hazy, colorless to yellow

SMILES string

NC(CCS(O)(=O)=O)C(O)=O

InChI

1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)

InChI key

VBOQYPQEPHKASR-UHFFFAOYSA-N

General description

Complexes of DL-homocysteic acid with Na+, Cu2+, Zn2+ and Ni2+ has been synthesized. DL-Homocysteic acid induces oxidative stress in brain of immature rats.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Jaroslava Folbergrová et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 31(2), 123-130 (2012-12-15)
We have recently demonstrated the evidence of oxidative stress in brain of immature rats during seizures induced by DL-homocysteic acid (DL-HCA). The aim of the present study was to investigate the antioxidant defense mechanisms under these conditions. Seizures were induced
Hui-Zhen Jia et al.
Guang pu xue yu guang pu fen xi = Guang pu, 27(7), 1291-1294 (2007-10-20)
The complexes of DL-homocysteic acid (DLH) with Na+, Cu2+, Zn2+ and Ni2+ were synthesized and elemental analyses were used to detect the compositions of these complexes. FTIR spectroscopy was employed to study these coordination structures. The results indicated that all
Glauber S F da Silva et al.
Frontiers in physiology, 8, 452-452 (2017-07-18)
Hydrogen Sulfide (H
Hari H Subramanian
The Journal of physiology, 591(1), 109-122 (2012-11-07)
Emotional reactions such as vocalization take place during expiration, and thus expression of emotional behaviour requires a switch from inspiration to expiration. I investigated how the midbrain periaqueductal grey (PAG), a known behavioural modulator of breathing, influences the inspiratory-to-expiratory phase
Hari H Subramanian et al.
Journal of neurophysiology, 105(6), 2852-2862 (2011-04-01)
Studies on brain stem respiratory neurons suggest that eupnea consists of three phases: inspiration, postinspiration, and expiration. However, it is not well understood how postinspiration is organized in the diaphragm, i.e., whether postinspiration differs in the crural and costal segments
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