Skip to Content
Merck
All Photos(1)

Key Documents

L1635

Sigma-Aldrich

L-Leucine β-naphthylamide

Synonym(s):

L-Leucine-2-naphthylamide

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C16H20N2O
CAS Number:
Molecular Weight:
256.34
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83

Assay

≥98% (TLC)

form

powder

solubility

H2O: insoluble

storage temp.

−20°C

SMILES string

CC(C)C[C@H](N)C(=O)Nc1ccc2ccccc2c1

InChI

1S/C16H20N2O/c1-11(2)9-15(17)16(19)18-14-8-7-12-5-3-4-6-13(12)10-14/h3-8,10-11,15H,9,17H2,1-2H3,(H,18,19)/t15-/m0/s1

InChI key

JWHURRLUBVMKOT-HNNXBMFYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

L-Leucine β-naphthylamide has been used as a substrate:
  • to measure the activity of aminopeptidase in Escherichia coli
  • to evaluate the enzyme activity of cathepsin H from rabbit skeletal muscles
  • in the proteolytic assay of L-Leucine aminopeptidase

Substrate for leucine aminopeptidase determination in colorimetric and histochemical procedures.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Quality

Very low free β-naphthylamine.

Substrates

Substrate for aminopeptidase M

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Aminopeptidase (arylamidase) activity in discrete areas of the rat brain: sex differences.
J M de Gandarias et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 21(5), 285-286 (1989-05-01)
Masanori Matsuishi et al.
The international journal of biochemistry & cell biology, 35(4), 474-485 (2003-02-05)
Rabbit muscle cathepsin H classified as an aminoendopeptidase was purified and its properties were investigated to clarify its contribution to the proteolysis of postmortem muscle. The purification was performed by ammonium sulfate fractionation and successive chromatographies on Sephadex G-75, phosphocelluose
T Nishimura et al.
European journal of biochemistry, 137(1-2), 23-27 (1983-12-01)
The mode of action towards oligopeptides and proteins of hydrolase H purified from rabbit skeletal muscle was studied. The presence of protamine or alpha-N-benzoylarginine p-nitroanilide (an endopeptidase substrate) changed both the Km and V values of the enzyme towards Leu-beta-naphthylamide
J M de Gandarias et al.
Journal of biochemical toxicology, 7(3), 171-175 (1992-01-01)
Carbon disulfide, a volatile solvent, is widely used in industry. It has been demonstrated that it causes several neuropsychological symptoms. However, the neurochemical basis of its neurotoxic effect is relatively unknown. In this paper we have measured the effect of
Proteolytic activity in the placenta, decidua and postimplantation embryos of the rat.
A Fein et al.
Israel journal of medical sciences, 21(4), 394-396 (1985-04-01)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service