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C7477

Sigma-Aldrich

L-Cysteine hydrochloride

≥98.0%, suitable for cell culture, BioReagent, non-animal source

Synonym(s):

(2R)-2-Amino-3-sulfanylpropanoic acid hydrochloride

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About This Item

Linear Formula:
HSCH2CH(NH2)COOH · HCl
CAS Number:
52-89-1
Molecular Weight:
157.62
Beilstein:
3560277
EC Number:
200-157-7
MDL number:
MFCD00064553
UNSPSC Code:
12352209
PubChem Substance ID:
24892963
NACRES:
NA.26
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Product Name

L-Cysteine hydrochloride, anhydrous, from non-animal source, BioReagent, suitable for cell culture, ≥98.0%

biological source

non-animal source

grade

anhydrous

product line

BioReagent

Assay

≥98.0%

form

powder or crystals

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white to off-white

mp

174.1-174.7 °C

solubility

H2O: 50 mg/mL

application(s)

peptide synthesis

SMILES string

Cl[H].N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S.ClH/c4-2(1-7)3(5)6;/h2,7H,1,4H2,(H,5,6);1H/t2-;/m0./s1

InChI key

IFQSXNOEEPCSLW-DKWTVANSSA-N

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Application

Non-animal source L-cysteine is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Biochem/physiol Actions

NMDA glutamatergic receptor agonist that is also an agonist at AMPA glutamatergic receptors at high concentrations.
NMDA glutamatergic receptor agonist; AMPA glutamatergic receptor agonist at high concentrations.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000426375
0000426375
BCCJ6572
BCCM4208
BCCL5357

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Claire Siebert et al.
PloS one, 15(2), e0228591-e0228591 (2020-02-06)
Biofilms are currently considered as a predominant lifestyle of many bacteria in nature. While they promote survival of microbes, biofilms also potentially increase the threats to animal and public health in case of pathogenic species. They not only facilitate bacteria
Natalya Yu Khromova et al.
Microorganisms, 10(2) (2022-02-26)
The health benefits of probiotics are beyond doubt. The positive effects of lactobacilli and bifidobacteria on the function of many body systems have been repeatedly proven by various studies. To completely realize the potential of probiotic microorganisms, the strains should
Soon Hee Kim et al.
Nature protocols, 16(12), 5484-5532 (2021-10-31)
The development of biocompatible and precisely printable bioink addresses the growing demand for three-dimensional (3D) bioprinting applications in the field of tissue engineering. We developed a methacrylated photocurable silk fibroin (SF) bioink for digital light processing 3D bioprinting to generate
Nynke Talma et al.
Aging cell, 20(10), e13450-e13450 (2021-10-02)
Cells expressing high levels of the cyclin-dependent kinase (CDK)4/6 inhibitor p16 (p16High ) accumulate in aging tissues and promote multiple age-related pathologies, including neurodegeneration. Here, we show that the number of p16High cells is significantly increased in the central nervous
Sabine A Tanner et al.
The British journal of nutrition, 114(5), 746-755 (2015-08-28)
Modulating the gut microbiota via dietary interventions is a common strategy to enhance the natural defence mechanisms of the host. Several in vitro studies have highlighted the probiotic potential of Bifidobacterium thermophilum RBL67 (RBL67) selected for its anti-Salmonella effects. The
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L-Cysteine in Cell Culture

Importance and uses of cysteine in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

L-Cysteine in Cell Culture

Importance and uses of cysteine in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

L-Cysteine in Cell Culture

Importance and uses of cysteine in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

L-Cysteine in Cell Culture

Importance and uses of cysteine in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Is there a way to enhance the stability of product C7477?

    1 answer

    1. This product is considered very stable. Keep C7477 away from moisture, air, and light.

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