A8679
Anti-Aflatoxin B1 antibody produced in rabbit
fractionated antiserum, buffered aqueous solution
Synonym(s):
Anti-Aflatoxin B1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
fractionated antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
technique(s)
capture ELISA: 1:4,000 using aflatoxin B1-BSA
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
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General description
Aflatoxin B1 is the most abundant and significant member of the group, which includes B2, B2a, G1, G2a, M1, M2, P1, Q1, aflatoxicol I (natural isomer), aflatoxicol II (unnatural isomer), tetrahydrodeoxy aflatoxin B1, and the unstable reactive B1 (8,9)-epoxide.
Aflatoxins are highly carcinogenic.
Aflatoxins are highly toxic mycotoxins produced by the fungus Aspergillus. Aflatoxins are commonly found in various grains and peanut butter.
Mycotoxins, a group of chemically diverse secondary fungal metabolites, induce a variety of toxic responses in humans and animals when food and feed containing these compounds are ingested. Rapidly quantitating levels of mycotoxin contamination can help reduce exposure to these toxins.
The antibody reacts with the B1 aflatoxin and also recognizes aflatoxins G1, B2, and the KLH protein. No cross-reaction is observed with aflatoxins and B2a, G2, G2a, M1.
Specificity
Sensitivity range for this product is 0.005-20 ng/ml of aflatoxin B1.
Immunogen
aflatoxin B1-KLH.
Application
Rabbit Anti-Aflatoxin B1 antibody has been used for the development of electrochemical immunosensors. The antibody has also been used in designing novel sandwich immunoassays. The product can also be used for capture ELISA at a dilution of 1:1,000.
Biochem/physiol Actions
Aflatoxin B1 and its metabolites act as potent carcinogens, mutagens and teratogens. Aflatoxins have been implicated in human hepatocellular carcinoma, outbreaks of aflatoxicosis, Rey′s syndrome, chronic hepatitis and increased mortality from infection in animal husbandry.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Jeong Moon et al.
Sensors (Basel, Switzerland), 18(2) (2018-02-22)
Aflatoxins (AFs) are highly toxic compounds that can cause both acute and chronic toxicity in humans. Aflatoxin B1 (AFB1) is considered the most toxic of AFs. Therefore, the rapid and on-site detection of AFB1 is critical for food safety management.
An over review on effect of aflatoxin in animal husbandry
Talebi E, et al.
Asian journal of experimental biological sciences, 2(3), 754-757 (2011)
C G Caratsch et al.
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Joseph H O Owino et al.
Analytical and bioanalytical chemistry, 388(5-6), 1069-1074 (2007-06-15)
Aflatoxins are a group of mycotoxins that have deleterious effects on humans and are produced during fungal infection of plants or plant products. An electrochemical immunosensor for the determination of aflatoxin B(1) (AFB(1)) was developed with AFB(1)antibody (AFB(1)-Ab) immobilized on
Wenqiang Lai et al.
Biosensors & bioelectronics, 89(Pt 1), 645-651 (2016-01-05)
A new colorimetric immunosensing platform accompanying enzyme cascade amplification strategy was fabricated for quantitative screening of small-molecular mycotoxins (aflatoxin B1, AFB1 used in this case) coupling with enzyme-controlled dissolution of MnO2 nanoflakes. The visual colored assay was executed by high-efficient
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