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Key Documents

A7791

Sigma-Aldrich

N-Acetyl-D-lactosamine

≥98% (TLC)

Synonym(s):

β-D-Gal-(1→4)-D-GlcNAc, 2-Acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucopyranose, LN, N-Acetyl-4-O-(β-D-galactopyranosyl)-D-glucosamine

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About This Item

Empirical Formula (Hill Notation):
C14H25NO11
CAS Number:
32181-59-2
Molecular Weight:
383.35
Beilstein:
96808
MDL number:
MFCD00063785
UNSPSC Code:
12352201
PubChem Substance ID:
24891280
NACRES:
NA.25

Assay

≥98% (TLC)

form

powder

optical activity

[α]25/D 27.5 to 33.5 °, c = 0.5% (w/v) in water

technique(s)

thin layer chromatography (TLC): suitable

impurities

≤8% water

color

white

mp

170 -185  °C ((338 - 365 °F ))

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

storage temp.

−20°C

SMILES string

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@@H]1O

InChI

1S/C14H25NO11/c1-4(18)15-7-9(20)12(6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8+,9-,10+,11-,12-,13?,14+/m1/s1

InChI key

KFEUJDWYNGMDBV-RPHKZZMBSA-N

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Application

N-Acetyl-D-lactosamine is used as a specific lectin target molecule in the identification and differentiation of sugar binding molecules such as the galectins. N-Acetyl-D-lactosamine is used in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.
Useful in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.

Preparation Note

Synthetic

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Frank Liang et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 25(12), 2635-2647 (2017-09-30)
mRNA vaccines are rapidly emerging as a powerful platform for infectious diseases because they are well tolerated, immunogenic, and scalable and are built on precise but adaptable antigen design. We show that two immunizations of modified non-replicating mRNA encoding influenza
Fumi Kato et al.
Breast cancer (Tokyo, Japan), 26(5), 628-636 (2019-04-03)
We investigated the usefulness of the minimum ADC value of primary breast lesions for predicting axillary lymph node (LN) status in luminal A-like breast cancers with clinically negative nodes in comparison with the mean ADC. Forty-four luminal A-like breast cancers
Cen Chen et al.
Materials science & engineering. C, Materials for biological applications, 103, 109865-109865 (2019-07-28)
Iridium (Ir) thin film was deposited on patterned titanium substrate by direct-current (DC) magnetron sputtering, and then activated in sulfuric acid (H2SO4) through repetitive potential sweeps to form iridium oxide (IrOx) as neural electrode interface. The resultant IrOx film showed
Fumiko Suenaga et al.
Journal of immunology (Baltimore, Md. : 1950), 194(1), 398-406 (2014-11-26)
Graft-versus-host disease (GVHD) is a major risk factor for prolonged humoral immunodeficiency and vaccine unresponsiveness after allogeneic hematopoietic stem cell transplantation (allo-HSCT). However, the underlying mechanisms for this immunodeficiency are poorly understood. In this article, we describe previously overlooked impacts
Lital Sever et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(33), 16489-16496 (2019-07-28)
SLAMF9 belongs to the conserved lymphocytic activation molecule family (SLAMF). Unlike other SLAMs, which have been extensively studied, the role of SLAMF9 in the immune system remained mostly unexplored. By generating CRISPR/Cas9 SLAMF9 knockout mice, we analyzed the role of
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