A6969

L-Arginine monohydrochloride

98.5-101.0%, suitable for cell culture, not synthetic, meets EP, JP, USP testing specifications

• Synonym(s): (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride, (S)-(+)-Arginine hydrochloride
• Empirical Formula (Hill Notation): C₆H₁₄N₄O₂ · HCl
• CAS Number: 1119-34-2
• Molecular Weight: 210.66
• Beilstein: 3631658
• EC Number: 214-275-1
• MDL number: MFCD00064550
• UNSPSC Code: 12352209
• PubChem Substance ID: 24891160
• NACRES: NA.26

Properties

• Product Name: L-Arginine monohydrochloride, not synthetic, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%
• Agency: USP/NF; meets EP testing specifications; meets JP testing specifications; meets USP testing specifications
• Assay: 98.5-101.0%
• form: powder
• optical activity: [α]20/D 22.1 to 22.9°, c = 8 in 6 M HCl
• quality: meets EP, JP, USP testing specifications
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white
• mp: 226-230 °C
• solubility: water: 100 mg/mL, clear, colorless
• density: 1.42 g/cm³ at 20 °C
• anion traces: chloride (Cl^-): 16.58-17.00%; sulfate (SO₄^2-): ≤0.020%
• cation traces: As: ≤1 ppm; Fe: ≤10 ppm; NH₄⁺: ≤0.02%; heavy metals: ≤10 ppm
• application(s): pharmaceutical (small molecule)
• functional group: (Guanidine); amine; carboxylic acid
• storage temp.: room temp
• SMILES string: Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O
• InChI: 1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1
• InChI key: KWTQSFXGGICVPE-WCCKRBBISA-N

Description

General description

L-arginine monohydrochloride is the hydrochloride salt form of L-arginine, an essential amino acid that plays a crucial role in several biological processes. It is commonly used in biology and biochemistry research as a cell culture supplement to support the growth and maintenance of various cell types.

Application

L-Arginine monohydrochloride has been used in mouse pancreas perfusion experiments.[1] It has also been used as a component of SILAC medium.[2]

Biochem/physiol Actions

L-Arginine is a dibasic, semi-essential amino acid. It acts as a precursor for creatinine and is a natural constituent of most of the dietary proteins.[3]

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Features and Benefits

• Suitable for Cell Culture and Biochemical research
• High-quality compound suitable for multiple research applications

Other Notes

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Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves