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96144

Sigma-Aldrich

Hyaluronic acid sodium salt from Streptococcus equi

mol wt 70,000-120,000

Synonym(s):

Sodium hyaluronate

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

(Streptococcus equi)

form

powder

mol wt

70,000-120,000

color

white

solubility

water: ~5 g/L

shipped in

wet ice

storage temp.

−20°C

InChI

1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1

InChI key

YWIVKILSMZOHHF-QJZPQSOGSA-N

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Application

Hyaluronic acid, an anionic, nonsulfated glycosaminoglycan (GAG), may be used in research involving processes such as inflammation, cell signaling, cell migration, cell differentiation, tissue engineering and wound-healing. Hyaluronic acid may be used as a substrate to identify and characterized catabolizing enzymes such as hyaluronidase(s). Hyaluronic acid may be used in biomaterials research for the development of biological scaffolds for wound-healing applications and hyaluronic acid fillers in human skin.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Natalie Fiander
British journal of nursing (Mark Allen Publishing), 22(9), S26-S26 (2013-06-12)
Painful bladder syndrome (PBS) and interstitial cystitis (IC) are associated with bladder pain, increased urinary frequency, urgency and reduced quality of life. The cause is still unknown, although there are several possible hypotheses. PBS/IC may significantly impact all areas of
Treatment of hyaluronan accumulation ameliorates high-fat diet-induced insulin resistance in mice.
Per Fogelstrand et al.
Diabetes, 62(6), 1816-1817 (2013-05-25)
Leena Rauhala et al.
The Journal of biological chemistry, 288(25), 17999-18012 (2013-05-07)
Hyaluronan, a major epidermal extracellular matrix component, responds strongly to different kinds of injuries. This also occurs by UV radiation, but the mechanisms involved are poorly understood. The effects of a single ultraviolet B (UVB) exposure on hyaluronan content and
Shenglian Yao et al.
Journal of nanoscience and nanotechnology, 13(7), 4752-4758 (2013-08-02)
Nanofibers exist ubiquitously in natural extracellular matrix (ECM) of all kinds of human tissues forming hydrated interwoven network. Electrospinning nanotechnology has been proven to be a powerful technique to fabricate controllable nanofibers mimicking the natural ECM structures. Hyaluronic acid (HA)
Daniela Elena Costea et al.
Cancer research, 73(13), 3888-3901 (2013-04-20)
Heterogeneity of carcinoma-associated fibroblasts (CAF) has long been recognized, but the functional significance remains poorly understood. Here, we report the distinction of two CAF subtypes in oral squamous cell carcinoma (OSCC) that have differential tumor-promoting capability, one with a transcriptome

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