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About This Item
Empirical Formula (Hill Notation):
C6H15O9P · xLi+
CAS Number:
Molecular Weight:
262.15 (free acid basis)
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25
Recommended Products
Quality Level
Assay
≥95% (TLC)
form
powder
color
white
storage temp.
−20°C
SMILES string
[P](=O)(OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)(O)O
InChI
1S/C6H15O9P/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14/h3-11H,1-2H2,(H2,12,13,14)/t3-,4-,5-,6-/m1/s1
InChI key
GACTWZZMVMUKNG-KVTDHHQDSA-N
Application
Mannitol-1-P can be used to detect the transphosphorylation activity of D-mannitol-specific enzyme II expreβed in spheroplasts.
Biochem/physiol Actions
D-Mannitol 1-phosphate is an intermediate in the fructose and mannose metabolism. It takes part in the phosphoenolpyruvate-dependent PEP group translocation (phosphotransferase system or PTS), a major mechanism used by bacteria for carbohydrate uptake.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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F F Roossien et al.
Biochemistry, 23(21), 4934-4939 (1984-10-09)
Purified mannitol-specific enzyme II (EIImtl), in the presence of the detergent Lubrol, catalyzes the phosphorylation of mannitol from P-HPr via a classical ping-pong mechanism involving the participation of a phosphorylated EIImtl intermediate. This intermediate has been demonstrated by using radioactive
Enzymes II of the phosphoenolpyruvate-dependent sugar transport systems: a review of their structure and mechanism of sugar transport.
G T Robillard et al.
Biochimica et biophysica acta, 947(3), 493-519 (1988-10-11)
H Rosenberg et al.
Journal of bacteriology, 158(1), 63-68 (1984-04-01)
The phosphate moiety of D-mannitol-1-phosphate in Escherichia coli is subject to rapid turnover and is in close equilibrium with Pi and the phosphorus of fructose-1,6-bisphosphate. These three compounds account for the bulk of 32P label found in cells after several
Stefan Krahulec et al.
Carbohydrate research, 343(9), 1414-1423 (2008-05-03)
A putative long-chain mannitol-1-phosphate 5-dehydrogenase from Aspergillus fumigatus (AfM1PDH) was overexpressed in Escherichia coli to a level of about 50% of total intracellular protein. The purified recombinant protein was a approximately 40-kDa monomer in solution and displayed the predicted enzymatic
K G Edwards et al.
Journal of bacteriology, 146(3), 1020-1029 (1981-06-01)
Mannitol (Mtl), not previously reported as an intracellular component of bacteria, although it has been found as an extracellular end product of anaerobic carbohydrate metabolism, accumulated within strains of all 10 staphylococcal species tested after aerobic incubation of washed cell
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