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55540

Sigma-Aldrich

4-(Hydroxymercuri)benzoic acid sodium salt

≥95.0% (Hg)

Synonym(s):

p-Chloromercuribenzoate, p-Hydroxymercuribenzoic acid sodium salt, PCMB, Sodium 4-(hydroxymercurio)benzoate

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About This Item

Empirical Formula (Hill Notation):
C7H5HgNaO3
CAS Number:
138-85-2
Molecular Weight:
360.69
Beilstein:
6118796
EC Number:
205-340-5
MDL number:
MFCD00002527
UNSPSC Code:
12352103
PubChem Substance ID:
57651536
NACRES:
NA.25

Assay

≥95.0% (Hg)

mp

≥300 °C

SMILES string

[Na+].O[Hg]c1ccc(cc1)C([O-])=O

InChI

1S/C7H5O2.Hg.Na.H2O/c8-7(9)6-4-2-1-3-5-6;;;/h2-5H,(H,8,9);;;1H2/q;2*+1;/p-2

InChI key

CBELQCYFTSHKPJ-UHFFFAOYSA-L

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Application

4-(Hydroxymercuri)benzoic acid is an organic mercurial compound that reacts via mercury-sulfur affinity with sulfhydryl groups in peptides, proteins and other molecules. PCMB may be used for the determination of sulfhydryl groups in proteins according to Boyer, by atomic absorption, and stopped-flow measurements, G. Castronuovo-Lepore et al.. It may be used for specific applications such as probing the active site of an enzyme such as cytochrome C oxidase. 4-(Hydroxymercuri)benzoic acid appeared mistakenly as p-chloromercuriobenzoate [PCMB] in earlier literature.

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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