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Supelco

Fumonisin B2 solution

~50 μg/mL in acetonitrile: water (50:50), analytical standard

Synonym(s):

FB2

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About This Item

Empirical Formula (Hill Notation):
C34H59NO14
CAS Number:
Molecular Weight:
705.83
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

shelf life

limited shelf life, expiry date on the label

concentration

~50 μg/mL in acetonitrile: water (50:50)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

CCCC[C@@H](C)[C@@H](OC(=O)C[C@@H](CC(O)=O)C(O)=O)[C@H](C[C@@H](C)CCCCCC[C@@H](O)C[C@H](O)[C@H](C)N)OC(=O)C[C@@H](CC(O)=O)C(O)=O

InChI

1S/C34H59NO14/c1-5-6-12-21(3)32(49-31(43)18-24(34(46)47)16-29(40)41)27(48-30(42)17-23(33(44)45)15-28(38)39)14-20(2)11-9-7-8-10-13-25(36)19-26(37)22(4)35/h20-27,32,36-37H,5-19,35H2,1-4H3,(H,38,39)(H,40,41)(H,44,45)(H,46,47)

InChI key

UXDPXZQHTDAXOZ-UHFFFAOYSA-N

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General description

Certan Vial
Fumonisin B2 belongs to the family of toxins known as fumonisins. It is produced by several species of Fusarium molds primarily by Fusarium verticillioide. It is one of the major mycotoxin contaminant in corn and corn-based foods. Fumonisin B2 is a structural analog of fumonisin B1 but it is more cytotoxic than the latter and it inhibits sphinganine-N-acetyltransferase (ceramide synthase).
Fumonisin B2 is a carcinogenic mycotoxin generally present on corn based food and feed-stuff, which is produced by the fungus Fusarium verticillioides and Fusarium moniliforme. Fumonisin B2 can also be detected in the industrially important fungi, Aspergillus niger.

Application

Fumosin B2 maybe used to study the effect of temperatures from ambient to 150°C and solvent compositions (methanol-water, acetonitrile-methanol-water, ethanol-water, and 100% water) on recovery of fumonisins from corn products.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Analysis Note

purity : ≥94.0% (HPLC)

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F

Flash Point(C)

2 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Occurrence of fumonisins B1 and B2 in corn-based products from the Swiss market
Pittet A, et al.
Journal of Agricultural and Food Chemistry, 40, 1352-1354 (1992)
Biomarkers in Toxicology.
Gupta RC.
Science, 555-556 (2014)
J F Lawrence et al.
Journal of AOAC International, 83(3), 604-611 (2000-06-27)
Fumonisins B1 and B2 were extracted from naturally contaminated corn products by using different extraction solvent compositions (methanol-water, acetonitrile-methanol-water, ethanol-water, and 100% water) and a range of temperatures from ambient to 150 degrees C. Ground samples of several corn products
Fumonisin B2 production by Aspergillus niger
Frisvad.AJ, et al.
Journal of Agricultural and Food Chemistry, 55, 9727-9732 (2007)
Jesper Mølgaard Mogensen et al.
Journal of industrial microbiology & biotechnology, 38(9), 1329-1335 (2010-12-07)
Tolypocladium inflatum is known primarily for its production of the cyclosporines that are used as an immunosuppressive drug. However, we report here the production of the carcinogenic fumonisins B(2) and B(4) by this biotechnologically relevant fungal genus. These mycotoxins were

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