Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

850350C

Avanti

15:0 PC

1,2-dipentadecanoyl-sn-glycero-3-phosphocholine, chloroform

Synonym(s):

PC(15:0/15:0)

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C38H76NO8P
CAS Number:
3355-27-9
Molecular Weight:
705.99
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850350C-25mg)
pkg of 2 × 4 mL (850350C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850350C

concentration

10 mg/mL (850350C-25mg)
25 mg/mL (850350C-200mg)

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C38H76NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-37(40)44-34-36(35-46-48(42,43)45-33-32-39(3,4)5)47-38(41)31-29-27-25-23-21-19-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/p+1

InChI key

LJARBVLDSOWRJT-UHFFFAOYSA-O

General description

Phosphatidylcholine (PC) carries a positively charged quaternary amine and a negatively charged phosphate in its headgroup. It is an important component of mammalian membranes.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

15:0 PC (1,2-dipentadecanoyl-sn-glycero-3-phosphocholine) may be used:
  • as a component in fluidizing lipid bilayers to study the role of membrane fluidity in mediating membrane sensitivity to small hydrophobic peptides or haptoglobin-related protein (SHP-1)
  • to prepare giant unilamellar lipid vesicles (GUVs)
  • to construct supported phospholipid bilayers to study the gel-fluid phase transition behavior using in situ, temperature-dependent atomic force microscopy

Biochem/physiol Actions

Phosphatidylcholine (PC) is capable of preventing the penetrance of bacteria by acting as a surfactant. This phospholipid is capable of forming a strong bilayer.

Packaging

5 mL Clear Glass Sealed Ampule (850350C-200mg)
5 mL Clear Glass Sealed Ampule (850350C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Thomas Andersen et al.
Soft matter, 10(24), 4268-4274 (2014-05-02)
We reveal that the gel to fluid phase transition causes spherical membrane vesicles to release a finite number of molecules in several consecutive and localized events. By locally melting Giant Unilamellar lipid Vesicles (GUVs), using an optically trapped gold nanoparticle
Z Vivian Feng et al.
Biophysical journal, 88(3), 2154-2164 (2004-12-15)
We utilize in situ, temperature-dependent atomic force microscopy to examine the gel-fluid phase transition behavior in supported phospholipid bilayers constructed from 1,2-dimyristoyl-sn-glycero-3-phosphocholine, 1,2-dipentadecanoyl-sn-glycero-3-phosphocholine, and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine. The primary gel-fluid phase transition at T(m) occurs through development of anisotropic cracks in the
Lipid-Protein Interactions in Membranes
The Membranes of Cells, 291-334 (2016)
M U Rasheed et al.
The Science of the total environment, 733, 139110-139110 (2020-05-25)
Increased soil nitrogen (N), warming and bark herbivory all are expected to affect boreal forests in the future. We studied the effects of warming (0.5 °C and 4.0 °C above ambient air and soil temperature, respectively), moderate N addition (30 kg N ha-1 y-1) and bark
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service