47624

Fmoc-Lys(Boc)-OH

≥98.0% (HPLC), for peptide synthesis

• Synonym(s): N_α-Fmoc-N_ε-Boc-L-lysine
• Empirical Formula (Hill Notation): C₂₆H₃₂N₂O₆
• CAS Number: 71989-26-9
• Molecular Weight: 468.54
• Beilstein: 4217767
• EC Number: 276-256-4
• MDL number: MFCD00037138
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57651044
• NACRES: NA.26

Properties

• Product Name: Fmoc-Lys(Boc)-OH, ≥98.0% (HPLC)
• Quality Level: 100
• Assay: ≥98.0% (HPLC)
• form: solid
• optical activity: [α]20/D −12±1°, c = 1% in DMF
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• application(s): peptide synthesis
• functional group: Boc; Fmoc
• storage temp.: 2-8°C
• SMILES string: CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
• InChI: 1S/C26H32N2O6/c1-26(2,3)34-24(31)27-15-9-8-14-22(23(29)30)28-25(32)33-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H,27,31)(H,28,32)(H,29,30)/t22-/m0/s1
• InChI key: UMRUUWFGLGNQLI-QFIPXVFZSA-N

Description

General description

Fmoc-Lys(Boc)-OH is an amino acid derivative used as a reagent in Fmoc solid-phase peptide synthesis.[1][2]

Application

Fmoc-Lys(Boc)-OH can be used for:

• The solid-phase synthesis of pentasubstituted dihydroimidazolylbutyl dihydroimidazol-3-ium salts by coupling with p-methylbenzhydrylamine (MBHA) resin.[3]
• Fmoc-based peptide synthesis of bis-naphthalene diimide, a threading intercalator.[4]
• Synthesis of ε-Boc-ε-(3,5-bis-trifluoromethyl-benzyl)-α-Fmoc-L-Lysine to be used as ¹⁹F NMR based screening tool.[5]

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves