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1604654

USP

Risperidone

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

R 64,766

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About This Item

Fórmula empírica (notación de Hill):
C23H27FN4O2
Número de CAS:
106266-06-2
Peso molecular:
410.48
Número MDL:
MFCD00274576
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329751052
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

risperidone

fabricante / nombre comercial

USP

aplicaciones

pharmaceutical (small molecule)

Formato

neat

cadena SMILES

CC1=C(CCN2CCC(CC2)c3noc4cc(F)ccc34)C(=O)N5CCCCC5=N1

InChI

1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3

Clave InChI

RAPZEAPATHNIPO-UHFFFAOYSA-N

Información sobre el gen

human ... DRD2(1813) , HTR2A(3356) , HTR2C(3358)

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Categorías relacionadas

Descripción general

Risperidone is a new central 5-hydroxytryptamine2 and dopamine D2 antagonist. It is used to treat agitation, aggression,and psychosis caused during demnetia. It is a neuroleptic drug. It is also an atypical antipsychotic drug which is used for treating schizophrenia.

Aplicación

It was used as reference standard during RP-UPLC analysis for determination of risperidone related compounds in Risperdal® Consta (risperidone long-acting injection).

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información legal

Risperdal is a registered trademark of Johnson & Johnson

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Referencia del producto
Descripción
Precios

1604665

Risperidone System Suitability Mixture, United States Pharmacopeia (USP) Reference Standard

R1000600

Risperidone, European Pharmacopoeia (EP) Reference Standard

Y0000370

Risperidone for system suitability, European Pharmacopoeia (EP) Reference Standard

1604676

Risperidone Related Compounds Mixture, United States Pharmacopeia (USP) Reference Standard

Y0001276

Risperidone impurity K, European Pharmacopoeia (EP) Reference Standard

1604756

Risperidone Related Compound G, United States Pharmacopeia (USP) Reference Standard

BP1137

Risperidone, British Pharmacopoeia (BP) Reference Standard

BP1158

Risperidone impurity standard, British Pharmacopoeia (BP) Reference Standard

Pictogramas

Skull and crossbones
GHS06

Palabra de señalización

Danger

Frases de peligro

H301

Consejos de prudencia

P301 + P330 + P331 + P310

Clasificaciones de peligro

Acute Tox. 3 Oral

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Development and Validation of RP-UPLC Method for Determination of Related Substances in Risperdal? Consta?.
Chen, Cheng-Tung, Cheng-Wei Cheng, and Yu-Fang Hu.
Journal of Chromatography and Separation Techniques, 6.6, 1-1 (2015)
Jérôme A J Becker et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(9), 2049-2060 (2014-03-13)
The etiology of Autism Spectrum Disorders (ASDs) remains largely unknown. Identifying vulnerability genes for autism represents a major challenge in the field and allows the development of animal models for translational research. Mice lacking the mu opioid receptor gene (Oprm1(-/-))
Christian Spang Pedersen et al.
Behavioural brain research, 273, 63-72 (2014-07-30)
Schizophrenia is a severe psychiatric disorder characterized by three symptom domains, positive (hallucinations, obsession), negative (social withdrawal, apathy, self-neglect) and cognitive (impairment in attention, memory and executive function). Whereas current medication ameliorates positive symptomatology, negative symptoms as well as cognitive
The D2 dopamine receptor occupancy of risperidone and its relationship to extrapyramidal symptoms: a PET study.
Kapur S
Life Sciences, 57(10), PL103-PL107 (1995)
Katherine Seto et al.
Therapeutic drug monitoring, 33(3), 275-283 (2011-03-26)
Although risperidone is commonly used in the acute and maintenance treatment of schizophrenia, the role of therapeutic drug monitoring has yet to be elucidated. The purpose of this review was to determine whether risperidone warrants therapeutic drug monitoring in patients
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