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Key Documents

1494909

USP

Pantoprazole Related Compound A

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Pantoprazole sulfone, 5-(Difluoromethoxy)-2-{[(3,4-dimethoxy-2-pyridinyl)methyl]sulfone}-1H-benzimidazole

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About This Item

Fórmula empírica (notación de Hill):
C16H15F2N3O5S
Número de CAS:
Peso molecular:
399.37
Beilstein/REAXYS Number:
9430498
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

pantoprazole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C16H15F2N3O5S/c1-24-13-5-6-19-12(14(13)25-2)8-27(22,23)16-20-10-4-3-9(26-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)

Inchi Key

FCJYMBZQIJDMMM-UHFFFAOYSA-N

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Application


  • Transcriptional profiling for drug repurposing in glioblastoma: This study utilized transcriptional profiling to identify therapeutic targets and repurpose drugs, including pantoprazole-related compounds, for treatment in glioblastoma. This approach underscores the utility of pantoprazole impurities in exploring new therapeutic avenues in pharmaceutical reference material research (Roddy et al., 2023).

  • Gastroprotective agent utilization: A drug utilization study in medicine and surgery wards highlighted the significant role of pantoprazole and its related compounds in managing gastrointestinal protection. This research emphasizes the importance of pantoprazole as a proton pump inhibitor and its impurities in ensuring the efficacy and safety of gastroprotective therapies (Koyani et al., 2023).

  • Synthesis and analysis of pantoprazole sodium sesquihydrate-related compound E: This study explored the synthesis and mechanism of formation of a specific pantoprazole-related compound, offering insights into the chemical stability and quality control of pantoprazole as a pharmaceutical ingredient. Such research is crucial for enhancing analytical methods in pharmaceutical research and ensuring drug safety and efficacy (Yari et al., 2019).

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

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Dafang Zhong et al.
The Journal of pharmacy and pharmacology, 57(3), 341-349 (2005-04-06)
We have investigated the metabolism of pantoprazole and have provided an explanation for the formation mechanism of its metabolites. Metabolites found in the urine of rats after oral administration of pantoprazole sodium (25 mg kg(-1)) were analysed by liquid chromatography/ion
E Doyle et al.
Journal of chromatography, 527(1), 67-77 (1990-04-27)
This paper describes two fully automated assays. One for zaprinast, a cGMP specific phosphodiesterase inhibitor, which uses the Gilson-Advanced Automated Sample Processor combination, and the other for an H+/K+ ATPase inhibitor and its sulphone metabolite, which uses direct injection. Both

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