1176007

Dexametasona

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: (11β,16α)-9-Fluoro-11,17,21-trihidroxi-16-metilpregna-1,4-dieno-3,20-diona, 9α-Fluoro-16α-metil-11β,17α,21-trihidroxi-1,4-pregnadieno-3,20-diona, 9α-fluoro-16α-metilprednisolona, Prednisolona F
• Fórmula empírica (notación de Hill): C₂₂H₂₉FO₅
• Número de CAS: 50-02-2
• Peso molecular: 392.46
• Beilstein: 2066651
• Número MDL: MFCD00064136
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329749548
• NACRES: NA.24

Propiedades

• origen biológico: synthetic
• grado: pharmaceutical primary standard
• Agency: USP
• presión de vapor: <0.0000001 kPa ( 25 °C)
• familia API: dexamethasone
• envase: pkg of 125 mg
• fabricante / nombre comercial: USP
• color: white
• mp: 262-264 °C (lit.)
• solubilidad: acetone: sparingly soluble; chloroform: slightly soluble; ethanol: sparingly soluble; ether: very slightly soluble; methanol: sparingly soluble; water: practically insoluble
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
• Clave InChI: UREBDLICKHMUKA-CXSFZGCWSA-N
• Información sobre el gen: human ... NR3C1(2908)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Dexamethasone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Ciprofloxacin and Dexamethasone Otic Suspension
• Dexamethasone
• Dexamethasone Compounded Oral Suspension
• Dexamethasone Elixir
• Dexamethasone Injection
• Dexamethasone Ophthalmic Suspension
• Dexamethasone Oral Solution

Acciones bioquímicas o fisiológicas

Glucocorticoide antiinflamatorio

Glucocorticoide antiinflamatorio. Regula la supervivencia, el crecimiento y la diferenciación de las células T. Inhibe la inducción de la óxido nítrico sintasa.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H360FD
• Consejos de prudencia: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Repr. 1B
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable