504971-40
Discovery® C18 (5 µm) HPLC Columns
L × I.D. 25 cm × 4 mm, HPLC Column
Sinónimos:
C18 TM=["Discovery"] HPLC Column
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Productos recomendados
product name
Columna para HPLC Discovery® C18, 5 μm particle size, L × I.D. 25 cm × 4 mm
material
stainless steel column
Quality Level
agency
suitable for USP L1
product line
Discovery®
feature
endcapped
manufacturer/tradename
Discovery®
packaging
1 ea of
extent of labeling
12% Carbon loading
parameter
≤70 °C temp. range
400 bar pressure (5801 psi)
technique(s)
HPLC: suitable
LC/MS: suitable
L × I.D.
25 cm × 4 mm
surface area
300 m2/g
surface coverage
3 μmol/m2
impurities
<10 ppm metals
matrix
silica gel, high purity, spherical particle platform
fully porous particle
matrix active group
C18 (octadecyl) phase
particle size
5 μm
pore size
180 Å
operating pH range
2-8
application(s)
food and beverages
separation technique
reversed phase
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General description
Utilice Discovery® C18 para cualquier método que especifique una C18. La forma del pico, la reproducibilidad y la estabilidad excepcionales hacen de ella la columna de elección para todos los métodos C18, desde los más exigentes hasta los rutinarios.
Application
- Identification, isolation and characterization of dolutegravir forced degradation products and their cytotoxicity potential.: Utilizes the Discovery® C18 HPLC Column to study the stability and degradation of the antiretroviral drug dolutegravir, crucial for ensuring drug safety and efficacy (Saida et al., 2019).
- Rapid, Refined, and Robust Method for Expression, Purification, and Characterization of Recombinant Human Amyloid beta 1-42.: This methodological study leverages the Discovery® C18 HPLC Column for the purification and analysis of amyloid beta peptides, contributing to research on Alzheimer′s disease (Prakash et al., 2019).
- Development and validation of a HPLC electrochemical detection method to measure COMT activity as a tool in drug development.: Showcases the use of the Discovery® C18 HPLC Column in developing a novel analytical method for measuring catechol-O-methyltransferase (COMT) activity, instrumental in the development of psychiatric and neurological medications (Viljoen et al., 2019).
Features and Benefits
- Excelente reproducibilidad
- Excepcional forma del pico para analitos básicos y ácidos
- Separaciones LC-MS estables con poco sangrado
- Separación de péptidos y proteínas pequeñas
- Menor hidrofobicidad que muchas columnas C 18 comparables, proporcionando análisis más rápidos
Legal Information
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
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Referencia del producto
Descripción
Precios
related product
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Contenido relacionado
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