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Z4402

Sigma-Aldrich

Zinterol hydrochloride

≥98% (HPLC)

Sinónimos:

Zinterol hydrochloride, N-[5-[2-[(1,1-dimethyl-2-phenylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]-Methanesulfonamide Hydrochloride; MJ 9184

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About This Item

Fórmula empírica (notación de Hill):
C19H26N2O4S·HCl
Número de CAS:
38241-28-0
Peso molecular:
414.95
Número MDL:
MFCD00867031
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
329831614
NACRES:
NA.77

Nivel de calidad

100

Ensayo

≥98% (HPLC)

Formulario

powder

condiciones de almacenamiento

desiccated

solubilidad

DMSO: ≥15 mg/mL

temp. de almacenamiento

room temp

cadena SMILES

CC(C)(Cc1ccccc1)NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2

InChI

1S/C19H26N2O4S/c1-19(2,12-14-7-5-4-6-8-14)20-13-18(23)15-9-10-17(22)16(11-15)21-26(3,24)25/h4-11,18,20-23H,12-13H2,1-3H3

Clave InChI

XJBCFFLVLOPYBV-UHFFFAOYSA-N

Acciones bioquímicas o fisiológicas

Zinterol Hydrochloride is a β2 adrenergic receptor selective agonist.

Características y beneficios

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Frases de peligro

H319

Clasificaciones de peligro

Eye Irrit. 2

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
051M4733V

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Dana S Hutchinson et al.
Naunyn-Schmiedeberg's archives of pharmacology, 373(2), 158-168 (2006-04-08)
The present study investigates the action of zinterol at beta(3)-adrenoceptors. We used mouse primary brown adipocytes and Chinese hamster ovary (CHO-K1) cells expressing the mouse or human beta(3)-adrenoceptor. Zinterol was a full agonist at increasing cyclic AMP levels in primary
S Magne et al.
The Journal of biological chemistry, 276(43), 39539-39548 (2001-08-17)
We have recently reported that arachidonic acid mediates beta(2)-adrenergic receptor (AR) stimulation of [Ca(2+)](i) cycling and cell contraction in embryonic chick ventricular cardiomyocytes (Pavoine, C., Magne, S., Sauvadet, A., and Pecker, F. (1999) J. Biol. Chem. 274, 628-637). In the
H E Lara et al.
Endocrine, 15(2), 187-192 (2001-11-27)
We investigated the possibility that norepinephrine from the human ovary is released after nerve stimulation and that this neurotransmitter is coupled to a steroidogenic response. Biologically significant levels of both norepinephrine and dopamine were found in human ovarian biopsies. [3H]norepinephrine
Ismayil Ahmet et al.
Circulation, 110(9), 1083-1090 (2004-08-18)
Studies in isolated cardiac myocytes have demonstrated that signaling via specific beta1-adrenergic receptor subtypes (beta1ARs) promotes but that signaling via beta2ARs protects from cell death. We hypothesized that prolonged beta(2)AR stimulation or beta1AR blockade would each protect myocytes from death
Susan F Steinberg et al.
American journal of physiology. Heart and circulatory physiology, 282(4), H1181-H1188 (2002-03-15)
We studied the role of beta-adrenergic receptor subtype signaling to cAMP and calcium in the genesis of catecholamine-dependent arrhythmias in German shepherd dogs that develop lethal arrhythmias at ~5 mo of age. There were three major findings in this study:
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β-Adrenoceptors

β-Adrenoceptors are activated either by norepinephrine or epinephrine. Learn more about the role of β-adrenoceptors in protein expression, cell signaling, and metabolism research.

β-Adrenoceptors

β-Adrenoceptors are activated either by norepinephrine or epinephrine. Learn more about the role of β-adrenoceptors in protein expression, cell signaling, and metabolism research.

β-Adrenoceptors

β-Adrenoceptors are activated either by norepinephrine or epinephrine. Learn more about the role of β-adrenoceptors in protein expression, cell signaling, and metabolism research.

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