WH0004790M1

Monoclonal Anti-NFKB1 antibody produced in mouse

clone 2E6, purified immunoglobulin, buffered aqueous solution

• Sinónimos: Anti-DKFZp686C01211, Anti-EBP1, Anti-KBF1, Anti-MGC54151, Anti-NFKBp105, Anti-NFKBp50, Anti-NFkappaB, Anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
• Número MDL: MFCD00802846
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 2E6, monoclonal
• Formulario: buffered aqueous solution
• reactividad de especies: human
• técnicas: indirect ELISA: suitable; indirect immunofluorescence: suitable; proximity ligation assay: suitable; western blot: 1-5 μg/mL
• isotipo: IgG1κ
• Nº de acceso GenBank: BC051765
• Nº de acceso UniProt: P19838
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... NFKB1(4790)

Descripción

Descripción general

NFKB1 (nuclear factor κB subunit 1) is a dimeric transcription factor. It belongs to the REL family. This gene is located on human chromosome 4q24.

Inmunógeno

NFKB1 (AAH51765, 860 a.a. ~ 969 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQEGPLEGKI

Acciones bioquímicas o fisiológicas

NFKB1 (nuclear factor κB subunit 1) controls the maturation of NK (natural killer) cells and effector functions. This gene helps in the upregulation of intrauterine adhesion inflammatory factors, hence NFKB1 plays a major role in inflammatory diseases.

Forma física

Solution in phosphate buffered saline, pH 7.4

Información legal

GenBank is a registered trademark of United States Department of Health and Human Services

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)