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Key Documents

U3510

Sigma-Aldrich

Universal Antibody Dilution Buffer, Ready-To-Use, with BSA

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About This Item

UNSPSC Code:
12352107
NACRES:
NA.47

pH

7.3-7.7

Quality Level

application(s)

hematology
histology

storage temp.

room temp

General description

Ready-to-use buffer for dilution of antibodies in all immunoassays. This buffer contains immunoglobulin free BSA and does not contain phosphate, sodium azide or mercury preservatives. It can be used for dilution of all antibodies, including peroxidase conjugates and antibodies to phosphoproteins. Not suitable for dilution of antibodies to S100 proteins.

Application

For dilution of primary or secondary antibodies. The diluted antibodies can be stored at 2-8 °C for several weeks.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Microglial activation plays central roles in neuroinflammatory and neurodegenerative diseases. Positron emission tomography (PET) targeting 18 kDa Translocator Protein (TSPO) is widely used for localising inflammation in vivo, but its quantitative interpretation remains uncertain. We show that TSPO expression increases in
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Cell cycle (Georgetown, Tex.), 17(9), 1146-1153 (2018-06-14)
The tumor suppressor p53 is a key regulator of cell apoptosis and cell cycle arrest. Recent studies show that the delicate balance of p53 expression is important for neural tube defects, neuronal degeneration, embryonic lethality, as well as differentiation and
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To monitor innate immune responses in the CNS, the 18 kDa Translocator protein (TSPO) is a frequently used target for PET imaging. The frequent assumption that increased TSPO expression in the human CNS reflects pro-inflammatory activation of microglia has been extrapolated

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