T9778

Tropicamide

solid

• Sinónimos: N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide, Ro 1-7683
• Fórmula empírica (notación de Hill): C₁₇H₂₀N₂O₂
• Número de CAS: 1508-75-4
• Peso molecular: 284.35
• EC Number: 216-140-2
• MDL number: MFCD00058580
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277879
• NACRES: NA.77

Propiedades

• form: solid
• Quality Level: 100
• color: white
• solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.3 mg/mL; ethanol: 5.6 mg/mL; H₂O: insoluble
• storage temp.: 2-8°C
• SMILES string: CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2
• InChI: 1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
• InChI key: BGDKAVGWHJFAGW-UHFFFAOYSA-N
• Gene Information: human ... CHRM3(1131) , CHRM4(1132)

Descripción

Application

Tropicamide has been used for studying the regulation of fragile X behavior in male mice. 1% tropicamide has also been used for dilating mice pupils.

Biochem/physiol Actions

M₄ muscarinic acetylcholine receptor antagonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

Tropicamide is soluble in 45% (w/v) aqueous 2-hydroxypropyl-beta-cyclodextrin (4.3 mg/mL) and ethanol (5.6 mg/mL).

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332,H315,H317,H319,H335
• pcodes: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable