The vial content for this product is determined on a lot-specific basis and is reported on the Certificate of Analysis. The minimum protein content will be 35 mg/vial. A brief review of recent lots shows the average of 39 mg/vial. See the links below to review several recent Certificates:
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/T9145-1VL0000255415.pdf
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/T9145-1VL-KCSLCN3202.pdf
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/T9145-1VLSLCM4718.pdf
T9145
Thyroglobulin from bovine thyroid
(For Gel Filtration Chromatography)
Sinónimos:
Tg
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About This Item
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Productos recomendados
origen biológico
bovine thyroid
Nivel de calidad
Formulario
powder
mol peso
~670 kDa
técnicas
bioconjugation: suitable
Nº de acceso UniProt
temp. de almacenamiento
−20°C
Información sobre el gen
cow ... TG(280706)
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Aplicación
Often used as a carrier protein for the production of antibodies. Its advantage is the large number of tyrosine residues that can be used for conjugation using the diazo reaction.
Thyroglobulin is used for antibody purification and characterization. Thyroglobulin has been used in studies assessing the monitoring of differentiated thyroid cancer as well as to develop an accurate diagnostic tool for patients with autoimmune thyroid diseases.
Acciones bioquímicas o fisiológicas
Iodine-containing protein that is stored in the thyroid gland. Converted into circulating thyroxines when the thyroid is stimulated by thyroid-stimulating hormone (TSH) from the pituitary. Because its expression is unique to the thyroid, it is a sensitive indicator of recurrence or metastasis of thyroid cancer that has been treated by thyroid ablation.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Certificados de análisis (COA)
Lot/Batch Number
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Kookjoo Kim et al.
Acta crystallographica. Section D, Structural biology, 77(Pt 11), 1451-1459 (2021-11-03)
Thyroglobulin is a homodimeric glycoprotein that is essential for the generation of thyroid hormones in vertebrates. Upon secretion into the lumen of follicles in the thyroid gland, tyrosine residues within the protein become iodinated to produce monoiodotyrosine (MIT) and diiodotyrosine
Andrew N Hoofnagle et al.
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Annales de biologie clinique, 69(6), 721-725 (2011-11-30)
Thyroglobuline (Tg) is a large molecule of high molecular weight mainly indicated in monitoring differentiated thyroid cancer (DTC), its measurement remains difficult. We report the case of a patient who underwent total thyroidectomy for a poorly differentiated thyroid insular carcinoma.
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Pendrin is an apical protein of thyroid follicular cells, responsible for the efflux of iodide into the follicular lumen via an iodide-chloride transport mechanism. It is unknown whether pendrin is recognized by autoantibodies. Our objective was to examine the prevalence
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Hello. Please, could you tell me the weight of powder in 1 vial of the product with catalog number T9145 (Thyroglobulin from bovine thyroid, 1VL). Thanks
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