T4009

Ácido taurocólico sodium salt hydrate

≥95% (HPLC)

• Sinónimos: Taurocolato de sodio hydrate, Ácido 2-[(3α,7α,12α-Trihidroxi-24-oxo-5β-colan-24-il) amino] etanosulfónico, Ácido 3α,7α,12α-trihidroxi-5β-colan-24-oico N-(sulfoetil)amida
• Fórmula empírica (notación de Hill): C₂₆H₄₄NNaO₇S · xH₂O
• Número de CAS: 345909-26-4
• Peso molecular: 537.68 (anhydrous basis)
• EC Number: 205-653-7
• MDL number: MFCD00150819
• UNSPSC Code: 12161900
• PubChem Substance ID: 24900186
• NACRES: NA.25

Propiedades

• biological source: synthetic (organic)
• Quality Level: 200
• description: anionic
• assay: ≥95% (HPLC)
• form: powder
• mol wt: micellar avg mol wt 2100
• aggregation number: 4
• CMC: 3-11 mM (20-25°C)
• functional group: sulfonic acid
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [Na+].[H]O[H].[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@H](CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS([O-])(=O)=O
• InChI: 1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1
• InChI key: RDAJAQDLEFHVNR-NEMAEHQESA-M

Descripción

General description

Taurocholic acid sodium salt hydrate is a bile acid with detergent capabilities.

Application

Taurocholic acid sodium salt hydrate has been used in a study to assess the adsorption of bile acids and salts to vegetable fibrous tissue. It has also been used in a study to investigate a method for determination of conjugated and unconjugated bile salts in serum and jejunal fluid.

Detergente aniónico utilizado para solubilización de proteínas.

Biochem/physiol Actions

Sal biliar no sulfatada, sustrato de transporte fisiológico para la bomba de exportación de sales biliares/hermana de Pgp (BSEP/spgp), cotransportador de Na⁽⁺⁾/taurocolato (NTCP) y MRP3 en los canalículos hepáticos.

Preparation Note

Synthesized from cholic acid

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)