T1505

Tetraisopropyl pyrophosphoramide

butyrylcholinesterase inhibitor

• Sinónimos: Tetra(monoisopropyl)pyrophosphortetramide, iso-OMPA
• Fórmula empírica (notación de Hill): C₁₂H₃₂N₄O₃P₂
• Número de CAS: 513-00-8
• Peso molecular: 342.36
• EC Number: 208-149-5
• MDL number: MFCD00048272
• UNSPSC Code: 12352202
• PubChem Substance ID: 24278724
• NACRES: NA.77

Propiedades

• biological source: synthetic
• mp: 149-151 °C
• storage temp.: −20°C
• SMILES string: CC(C)NP(=O)(NC(C)C)OP(=O)(NC(C)C)NC(C)C
• InChI: 1S/C12H32N4O3P2/c1-9(2)13-20(17,14-10(3)4)19-21(18,15-11(5)6)16-12(7)8/h9-12H,1-8H3,(H2,13,14,17)(H2,15,16,18)
• InChI key: IOIMDJXKIMCMIG-UHFFFAOYSA-N
• Gene Information: human ... ACHE(43) , BCHE(590)

Descripción

Application

Tetraisopropyl pyrophosphoramide has been used:

• as a butyrylcholinesterase inhibitor to determine the proportions of butyrylcholinesterase (BChE) in cat and tiger plasma
• to inhibit wild-type BChE in acetylcholinesterase assay
• to selectively block the enzymatic activity of AChE

Biochem/physiol Actions

Selective inhibitor of butyrylcholinesterase

Warning

WARNING: Extremely hazardous! Be aware of the risk and familiar with safety procedures before you use this product.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H310 + H330
• pcodes: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
• Storage Class: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges