SAB4502956

Anti-TGF β2, C-Terminal antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Cetermin, G-TSF, Polyergin, TGFB2, Transforming growth factor β-2
• MDL number: MFCD01634324
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 47 kDa
• species reactivity: mouse, rat, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:5000; immunohistochemistry: 1:50-1:100
• NCBI accession no.: P61812
• UniProt accession no.: P61812
• application(s): research pathology
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... TGFB2(7042)

Descripción

General description

Anti-TGF β2 Antibody detects endogenous levels of total TGF β2 protein.

Transforming growth factor-β2 (TGFB2) gene codes for the transforming growth factor β2 (TGFβ2).( β (TGF-β) protein superfamily. TGFB2 gene is mapped to human chromosome 1q41.

Immunogen

The antiserum was produced against synthesized peptide derived from human TGF beta2.

Immunogen Range: 361-410

Application

Anti-TGF β2, C-Terminal antibody produced in rabbit has been used in western blotting.

Biochem/physiol Actions

Transforming growth factor-β2 (TGFB2) protein plays a key role in transforming growth factor-β (TGF-β) signaling pathway. It aids in binding several TGF-β receptors to recruit and stimulate the others against decapentaplegic homolog SMAD protein family. TGF-β2 is involved in the proliferation and metastasis of glioma cells. It is implicated in metabolic syndrome (MetS). Single-nucleotide polymorphisms (SNPs) in TGFB2 are also associated with end-stage renal disease and conotruncal heart defects.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable