SAB4500435

Anti-Claudin 3 antibody produced in rabbit

affinity isolated antibody

• Sinónimos: CPE-R 2, CPE-receptor 2, Claudin-3, Clostridium perfringens enterotoxin receptor 2, Ventral prostate.1 protein homolog
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 23 kDa
• species reactivity: rat, mouse, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:40000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: O15551
• UniProt accession no.: O15551
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CLDN3(1365)

Descripción

General description

Anti-Claudin 3 Antibody detects endogenous levels of total Claudin 3 protein.

Claudin-3 (CLDN3) is a tetraspanin transmembrane protein, that is mapped to human chromosome 7q11.23.

Immunogen

The antiserum was produced against synthesized peptide derived from human Claudin 3.

Immunogen Range: 171-220

Application

Anti-Claudin 3, C-Terminal antibody has been used in immunofluorescence and western blotting.

Biochem/physiol Actions

In submandibular gland, claudin-3 (CLDN3) controls paracellular permeability with the help of TNF-α(tumor necrosis factor α). High level expression of CLDN3 improves the malignant ability of colorectal cancer cells. It participates in the organization and activities of tight junctions (TJs).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable