S4776

Somatotropin from human pituitary

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder

• Sinónimos: STH
• Número MDL: MFCD00081960
• Código UNSPSC: 51111800
• NACRES: NA.32
• origen biológico: human
• Formulario: lyophilized powder
• Ensayo: ≥95% (SDS-PAGE)

Propiedades

• origen biológico: human
• Nivel de calidad: 200
• recombinante: expressed in E. coli
• esterilidad: non-sterile
• Ensayo: ≥95% (SDS-PAGE)
• Formulario: lyophilized powder
• potencia: 0.025-0.1 ng/mL cell proliferation using Nb2-11 cells per bioactivity ED₅₀
• mol peso: predicted mol wt ~22 kDa
• drug control: Home Office Schedule 4.2
• impurezas: endotoxin, tested
• solubilidad: PBS: 0.100 mL, clear, colorless (with 0.1% BSA )
• Nº de acceso UniProt: P01241; P10912
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... GH1(2688) , GHR(2690)

Descripción

Descripción general

Somatotropin or growth hormone is a peptide hormone that is secreted by the anterior pituitary gland. It is essential for growth. The hormone increases muscle mass, reduces fat mass, helps in maintaining normal blood glucose levels and also promotes a balanced lipid profile.

Aplicación

Somatotropin or growth hormone has been used to study the molecular interactions of ephrin type-A receptor 4 precursor (EphA4) with the growth hormone receptor. It has also been used to induce differentiation in mammary epithelial cell line HC11.

Acciones bioquímicas o fisiológicas

Increases mass of most tissues by increasing cell number rather than cell size, mobilizes fat stores.

Forma física

Lyophilized from a 0.2 μm filtered solution in TBS (20 mM Tris, 0.15 M NaCl, pH 8.5) containing 50 μg of BSA per 1 μg of cytokine.

Reconstitución

It is recommended that sterile PBS containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of no less than 10 μg/mL.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable