Saltar al contenido
Merck
Todas las fotos(2)

Key Documents

View All Documentation

RAB0458

Sigma-Aldrich

Human Thyroglobulin ELISA Kit

for serum, plasma, cell culture supernatants and urine

Sinónimos:

TGF-beta-1, Thyroglobulin

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(2)

About This Item

UNSPSC Code:
41116158
NACRES:
NA.77

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 220 pg/mL
standard curve range: 0.205-50 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TG(7038)

General description

The Human Thyroglobulin ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Thyroglobulin in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human Thyroglobulin

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human Thyroglobulin ELISA Kit has been used to measure the secreted thyroglobulin (TG) level in primary human thyrocytes.

Biochem/physiol Actions

Thyroglobulin (TG) is a prothyroid hormone. It plays a vital role in production of L-thyroxine (tetraiodothyronine, T4) and L-triiodothyronine (T3) hormones in thyroid gland. Tyrosyls of TG acts as substrate for iodination and hormone formation. Serum thyroglobulin level is used as marker of metastases in differentiated thyroid carcinomas. Mutation in the gene is associated with the development of congenital goitrous hypothyroidism and non-endemic simple goitre.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Kathleen M Aicher et al.
PloS one, 14(2), e0212638-e0212638 (2019-02-28)
Gallbladder mucocele formation is an emerging disease in dogs characterized by increased secretion of condensed granules of gel-forming mucin by the gallbladder epithelium and formation of an abnormally thick mucus that can culminate in obstruction of the bile duct or
Role of extracellular molecular chaperones in the folding of oxidized proteins refolding of colloidal thyroglobulin by protein disulfide isomerase and immunoglobulin heavy chain-binding protein.
Delom F, et al.
The Journal of Biological Chemistry, 276(24), 21337-21342 (2001)
Serum thyroglobulin and iodine-131 whole-body scan in the diagnosis and assessment of treatment for metastatic differentiated thyroid carcinoma.
Lubin E, et al.
Journal of Nuclear Medicine, 35(2), 257-262 (1994)
A nonsense mutation causes human hereditary congenital goiter with preferential production of a 171-nucleotide-deleted thyroglobulin ribonucleic acid messenger.
Targovnik H M, et al.
The Journal of Clinical Endocrinology and Metabolism, 77(1), 210-215 (1993)
Thyrotropin and insulin-like growth factor 1 receptor crosstalk upregulates sodium?iodide symporter expression in primary cultures of human thyrocytes.
Morgan S J, et al.
Thyroid, 26(12), 1794-1803 (2016)
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico