MAK110

MTP Activity Assay Kit

Supplied by Roar Biomedical, Inc.

• Sinónimos: MTTP Activity Assay Kit, Microsomal triglyceride transfer protein activity assay kit
• Código UNSPSC: 12161503
• NACRES: NA.84

Propiedades

• uso: sufficient for 100 fluorometric tests
• aplicaciones: pharmaceutical
• método de detección: fluorometric
• enfermedades relevantes: cardiovascular diseases
• temp. de almacenamiento: 2-8°C
• Información sobre el gen: human ... MTTP(4547)

Descripción

Descripción general

Microsomal triglyceride transfer protein (MTP), a membrane-bound protein present in the liver, plays an important role in the assembly and secretion of very low density lipoprotein (VLDL). MTP is also necessary for assembly and secretion of chylomicrons by the intestine. This protein facilitates the transfer of triglyceride (TG), cholesteryl ester (CE) and phosphatidylcholine (PC) between phospholipid surfaces. Mutation in the MTP gene leads to abetalipoproteinemia.

Aplicación

MTP Activity Assay Kit has been used to measure the activity of microsomal triglyceride transfer protein (MTP).

Características y beneficios

Compatible with high-throughput handling systems.

Idoneidad

Suitable for measuring microsomal [triglyceride] transfer protein (MTP) activity in cell lysates or tissue homogenates, or for screening MTP activity inhibitors.

Principio

The MTP Activity Assay Kit is a sensitive, homogeneous fluorometric assay useful for continuous measurement of MTP activity in cell lysate or tissue homogenate. This kit includes proprietary substrates that enable the detection of MTP-mediated transfer of neutral lipid. The transfer activity results in an increase in fluorescence intensity (λ_Ex=465 nm/λ_Em=535 nm).

Nota de análisis

Learn more about Roar Assay Kits for Studies in Lipoprotein Metabolism.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids