M6518

Macrophage Colony-Stimulating Factor human

≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Sinónimos: MCSF
• Número MDL: MFCD00166591
• Código UNSPSC: 12352202
• NACRES: NA.77

Propiedades

• Nombre del producto: Macrophage Colony-Stimulating Factor human, M-CSF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
• origen biológico: human
• Nivel de calidad: 200
• recombinante: expressed in E. coli
• Ensayo: ≥98% (SDS-PAGE and HPLC)
• Formulario: lyophilized powder
• potencia: 0.500-5.000 ng/mL ED₅₀
• calidad: endotoxin tested
• mol peso: dimer 37 kDa
• envase: pkg of 10 μg
• técnicas: cell culture | mammalian: suitable
• impurezas: ≤1.000 EU/μg
• color: white
• Nº de acceso UniProt: P09603
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... CSF1(1435)

Descripción

Descripción general

Macrophage Colony-Stimulating Factor (M-CSF) is a hematopoietic growth factor, which modulates the proliferation, differentiation and functional activation of monocytes. It is produced by fibroblasts, endothelial cells and bone marrow stromal cells. MCSF stimulates the functions of mature monocytes and macrophages.

Aplicación

Macrophage Colony-Stimulating Factor human has been used for the differentiation of bone marrow-derived macrophages (BMDMs) and human monocyte-derived macrophages (MDMs). It has also been used for cell culture.

Acciones bioquímicas o fisiológicas

Macrophage colony-stimulating factor (M-CSF) augments many of the physiological functions of macrophages, and support osteoclast differentiation.

Otras notas

159 amino acids including N-terminal methionine (each monomer).

Forma física

Lyophilized from a sterile filtered buffered solution.

Nota de análisis

The proliferative activity is tested in culture using the cytokine-dependent murine monocytic cell line M-NFS-60 cells.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)