M6034

IgG2a, Lambda from murine myeloma

clone HOPC-1, purified immunoglobulin, buffered aqueous solution

• Sinónimos: Mouse IgG2a-λ
• Número MDL: MFCD00164801
• Código UNSPSC: 12352203
• NACRES: NA.46

Propiedades

• origen biológico: mouse
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• clon: HOPC-1, monoclonal
• Formulario: buffered aqueous solution
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified

Descripción

Descripción general

An immunoglobulin has two heavy chain and two light chain connected by disulfide bond.[1] It is a glycoprotein. Rat has five immunoglobulin classes- IgM, IgG, IgA, IgD and IgGE.[2] Immunoglobulin G (IgG) is a major class of immunoglobulin. IgG has four subclasses- IgG1, IgG2a, IgG2b and IgG2c.[3]

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections[4]
IgG2a, λ from murine myeloma specifically recognizes mouse IgG2a. Specificity of the mouse IgG2a, λ is determined by immunodiffusion and IEP techniques. The purified myeloma preparation is non-reactive with antisera to mouse IgA, IgM, IgG1, IgG2a, IgG2b and IgG3.

Aplicación

IgG2a, Lambda from murine myeloma has been used to standardize the enzyme-linked immunosorbent assay (ELISA) assay.[5]

Acciones bioquímicas o fisiológicas

Immunoglobulin G (IgG) mainly helps in immune defense.[1] Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions.[6] It helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.[3]

Forma física

Solution in 0.02 M Tris buffered saline, pH 8.0, containing 0.02% sodium azide

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable