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Merck

M5760

Sigma-Aldrich

4-(4-Methoxybenzylamino)-7-nitrobenzofurazan

>97.5% purity (HPLC), powder

Sinónimos:

4-(4-Methoxybenzylamino)-7-nitro-2,1,3-benzoxadiazole, MBD

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About This Item

Fórmula empírica (notación de Hill):
C14H12N4O4
Número de CAS:
Peso molecular:
300.27
Beilstein/REAXYS Number:
1151390
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

4-(4-Methoxybenzylamino)-7-nitrobenzofurazan,

assay

>97.5% (HPLC)

Quality Level

form

powder

color

orange to red

solubility

DMSO:methanol (1:1): 50 mg/mL, clear, orange

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

COc1ccc(CNc2ccc([N+]([O-])=O)c3nonc23)cc1

InChI

1S/C14H12N4O4/c1-21-10-4-2-9(3-5-10)8-15-11-6-7-12(18(19)20)14-13(11)16-22-17-14/h2-7,15H,8H2,1H3

Inchi Key

IENONFJSMWUIQQ-UHFFFAOYSA-N

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Application

Fluorescent probe for hydrophobic (non-polar) regions in proteins and nucleoproteins.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Yu Nakamichi et al.
Scientific reports, 9(1), 6466-6466 (2019-04-25)
Despite extensive research on primate cognitive function, understanding how anatomical connectivity at a neural circuit level relates to information transformation across different cortical areas remains primitive. New technology is needed to visualize inter-areal anatomical connectivity in living monkeys and to
Benjamin C Buchmuller et al.
Scientific reports, 10(1), 4053-4053 (2020-03-07)
5-Methylcytosine (mC) exists in CpG dinucleotides of mammalian DNA and plays key roles in chromatin regulation during development and disease. As a main regulatory pathway, fully methylated CpG are recognized by methyl-CpG-binding domain (MBD) proteins that act in concert with
Sevda Tanrıkulu-Küçük et al.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 44(7), 774-782 (2019-01-04)
This study investigated the effects of curcumin and capsaicin on testicular and hepatic oxidant-antioxidant status in rats fed a high-fat diet (HFD). Male Sprague-Dawley rats were divided into 5 groups (8 rats per group). The control group was fed a
Ke Liu et al.
The FEBS journal, 286(16), 3240-3254 (2019-04-14)
The MBD3, a methyl-CpG-binding domain (MBD)-containing protein, is a core subunit of the Mi-2/NuRD complex. Recent reports show that MBD3 recognizes both methylated CG (mCG)- and hydroxymethylated CG (hmCG)-containing DNA, with a preference for hmCG. However, whether the MBD3-MBD indeed
Moayyad E Suleiman et al.
The British journal of radiology, 91(1085), 20180032-20180032 (2018-02-06)
This work proposes the use of mammographic breast density (MBD) to estimate actual glandular dose (AGD), and assesses how AGD compares to mean glandular dose (MGD) estimated using Dance et al method. A retrospective sample of anonymised mammograms (52,405) was

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