M3696

Anti-MAP2 Antibody

rabbit polyclonal

• Sinónimos: Anti-Microtubule associated protein 2
• Número MDL: MFCD00164683
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• Nombre del producto: Anti-MAP2 antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution
• origen biológico: rabbit
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen ~280 kDa; antigen ~72 kDa
• reactividad de especies: rat, mouse, human
• concentración: ~1 mg/mL
• técnicas: flow cytometry: 1:200-1:500; immunohistochemistry: 1:100-1:200; western blot: 1:500-1:1,000
• Nº de acceso UniProt: P11137
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... MAP2(4133) ; mouse ... Mtap2(17756) ; rat ... Map2(25595)

Descripción

Descripción general

MAP2 is a microtubule-associated protein that regulates the structure and function of the cytoskeleton. The protein also modulates morphogenesis of neurons and cell proliferation. Interactions of MAP2 with F-actin have been implicated in neurite initiation and microtubular re-organization. Decreased levels of MAP2 have been associated with transmissible spongiform encephalopathies . Anti-MAP2 antibody is specific for MAP2 in human, mice and rats.

Microtubule associated protein 2 (MAP2) is a neuron specific protein, which is highly expressed in the central nervous system. It is the member of cytoskeletal proteins. The gene is located on human chromosome 2q34.

Inmunógeno

synthetic peptide corresponding to residues 2-15 of human MAP2.

Aplicación

Anti-MAP2 antibody is suitable for use in immunohistochemistry (1:500 using Zamboni′s fixative-fixed, frozen mouse spinal cord and thalamus sections) , flow cytometry (1:200-1:500), immunoblotting (approx. 72 kDa and 280 kDa) and western blot (1:500-1:1,000).

Anti-MAP2 antibody produced in rabbit has been used in immunocytochemistry.

Acciones bioquímicas o fisiológicas

Microtubule associated protein 2 (MAP2) plays a critical role in the formation of dendritic protrusions in astrocytes and oligodendrocytes. It maintains the homeostasis of microtubules. The protein plays an important role in neuronal plasticity.

Forma física

solution in phosphate buffered saline, containing 0.02% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)