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Merck

H9262

Sigma-Aldrich

(Hydroxypropyl)methyl cellulose

viscosity 80-120 cP, 2 % in H2O(20 °C)(lit.)

Sinónimos:

2-Hydroxypropyl methyl cellulose ether

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About This Item

Número de CAS:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.56

form

powder

Quality Level

mol wt

~26 kDa

color

beige

viscosity

80-120 cP, 2 % in H2O(20 °C)(lit.)

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Application

(Hydroxypropyl)methyl cellulose acts as a thickener for aqueous and non-aqueous systems, is a water retention aid and steric stabilizer, and clear films with grease resistance. (Hydroxypropyl)methyl cellulose has been used to study mucoadhesion in the design of drug delivery systems to prolong intestinal residence time and has also been used to study the enhancement of dissolution rate of poorly water soluble drugs.
Thickener for aqueous and non-aqueous systems, clear films with grease resistance, binders, lubricants, steric stabilizer and water retention aid.

Features and Benefits

Dissolves in water, undergoes reversible gelation upon heating, non-ionic, does not complex with ionic species and is surface active and enzyme resistant. Solutions are pseudoplastic.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Deirdre M D'Arcy et al.
AAPS PharmSciTech, 20(2), 47-47 (2019-01-09)
Viscosity, influenced by medium composition, will affect the hydrodynamics of a dissolution system. Dissolution simulation methods are valuable tools to explore mechanistic dissolution effects, with an understanding of limitations of any simulation method essential to its appropriate use. The aims
Lucas Sievens-Figueroa et al.
International journal of pharmaceutics, 423(2), 496-508 (2011-12-20)
The design and feasibility of a simple process of incorporating stable nanoparticles into edible polymer films is demonstrated with the goal of enhancing the dissolution rate of poorly water soluble drugs. Nanosuspensions produced from wet stirred media milling (WSMM) were
Fernando Andrés et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(26), E2760-E2769 (2014-07-01)
In Arabidopsis thaliana environmental and endogenous cues promote flowering by activating expression of a small number of integrator genes. The MADS box transcription factor SHORT VEGETATIVE PHASE (SVP) is a critical inhibitor of flowering that directly represses transcription of these
Jeonghoon Han et al.
Aquatic toxicology (Amsterdam, Netherlands), 152, 308-317 (2014-05-13)
In this study, we investigated the effects of the water-accommodated fraction (WAF) of crude oil on the development and reproduction of the intertidal copepod Tigriopus japonicus through life-cycle experiments. Furthermore, we investigated the mechanisms underlying the toxic effects of WAF
Jane W Agger et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(17), 6287-6292 (2014-04-16)
The recently discovered lytic polysaccharide monooxygenases (LPMOs) are known to carry out oxidative cleavage of glycoside bonds in chitin and cellulose, thus boosting the activity of well-known hydrolytic depolymerizing enzymes. Because biomass-degrading microorganisms tend to produce a plethora of LPMOs

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