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H0392

Sigma-Aldrich

Hemoglobin S, Ferrous Stabilized human

lyophilized powder

Sinónimos:

Sickle cell hemoglobin

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About This Item

Número de CAS:
9035-22-7
Número MDL:
MFCD00131288
Código UNSPSC:
12352202
eCl@ss:
42030116
NACRES:
NA.61

origen biológico

human

Nivel de calidad

200

Ensayo

97-100% (agarose gel electrophoresis)

Formulario

lyophilized powder

técnicas

electrophoresis: suitable
immunofluorescence: suitable

solubilidad

H2O: soluble 20 mg/mL

idoneidad

suitable for electrophoresis and chromatography standard

Nº de acceso UniProt

P68871

temp. de almacenamiento

−20°C

Información sobre el gen

human ... HBB(3043)

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Descripción general

Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.
has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).

Aplicación

Hemoglobin S was used in the determination of fetal hemoglobin by time-resolved immunofluorometric assay.

Envase

Package size indicates the amount of hemoglobin as determined by the procedure of Drabkin, D.L., J. Biol. Chem., 164, 703 (1946).

Reconstitución

When reconstituted with buffer, gives >90% ferrous hemoglobin.

Cláusula de descargo de responsabilidad

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Aplicación

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
0000420145
0000420145
0000382365
0000382364
0000406272

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Brian T Castle et al.
Science advances, 5(3), eaau1086-eaau1086 (2019-03-21)
In sickle cell disease, the aberrant assembly of hemoglobin fibers induces changes in red blood cell morphology and stiffness, which leads to downstream symptoms of the disease. Therefore, understanding of this assembly process will be important for the treatment of
U Turpeinen et al.
Clinical chemistry, 38(10), 2013-2018 (1992-10-01)
We have developed a "sandwich"-type time-resolved immunofluorometric assay (IFMA) for fetal hemoglobin (HbF) in hemolysates from adults and newborns, amniotic fluid, and plasma, based on a polyclonal and a monoclonal antibody against human fetal hemoglobin. Microtiter wells are coated with
Charles T Quinn et al.
British journal of haematology, 175(4), 724-732 (2016-09-09)
Sickle cell disease (SCD) is a significant healthcare burden worldwide, but most affected individuals reside in low-resource areas where access to diagnostic testing may be limited. We developed and validated a rapid, inexpensive, disposable diagnostic test, the HemoTypeSC™ , based

Chromatograms

application for HPLC

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