GW21444

Anti-M6PR antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-Cation-dependent mannose-6-phosphate receptor
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: chicken
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: mouse, human, rat
• manufacturer/tradename: Genway 15-288-21444
• technique(s): immunocytochemistry: suitable; western blot: suitable
• NCBI accession no.: NP_002346.1
• UniProt accession no.: P20645
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... M6PR(4074)

Descripción

Immunogen

Immunogen Sequence: GI # 4505061, sequence 60-114

Recombinant cation-dependent mannose-6-phosphate receptor

Application

Anti-M6PR antibody produced in chicken is suitable for immunocytochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Mannose 6-phosphate receptor is an integral transmembrane glycoprotein encoded by the M6PR gene in humans. It is ubiquitously expressed and are distinguished from all other lectins by their ability to recognize phosphorylated mannose residues. It is a 46kDa cation-dependent mannose 6-phosphate receptor (CD-MPR) and plays a key role in the delivery of lysosomal enzymes to the lysosome by binding newly synthesized mannose 6-phosphate (Man-6-P)-containing acid hydrolases and diverting them from the secretory pathway. M6PR plays a major role in cellular function by transporting Man-6-P-containing acid hydrolases from the Golgi to endosomal/lysosomal compartments.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)