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Merck

C0125

Sigma-Aldrich

Cacodylic acid

≥98%

Sinónimos:

Dimethylarsinic acid, Dimethylarsonic acid, Hydroxydimethylarsine oxide

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About This Item

Fórmula lineal:
(CH3)2As(O)OH
Número de CAS:
Peso molecular:
138.00
Beilstein/REAXYS Number:
1736965
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

≥98%

form

powder

solubility

water: 50 mg/mL, clear, colorless

SMILES string

C[As](C)(O)=O

InChI

1S/C2H7AsO2/c1-3(2,4)5/h1-2H3,(H,4,5)

InChI key

OGGXGZAMXPVRFZ-UHFFFAOYSA-N

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Monika K Nisiewicz et al.
International journal of molecular sciences, 22(1) (2021-01-08)
Nearly half of patients with advanced and metastatic melanomas harbor a BRAF mutation. Vemurafenib (VEM), a BRAF inhibitor, is used to treat such patients, however, responses to VEM are very short-lived due to intrinsic, adaptive and/or acquired resistance. In this
Fang-Chih Chang et al.
Talanta, 198, 137-145 (2019-03-17)
An analytical method for the biomonitoring of arsenic, benzene and polycyclic aromatic hydrocarbons (PAHs) in human urine was developed using liquid chromatography tandem mass spectrometry (LC-MS/MS). The urinary metabolites of monomethylarsonic acid (MMAA), dimethylarsonic acid (DMAA), s-phenylmercapturic acid (S-PMA), and
S Yamamoto et al.
Mutation research, 386(3), 353-361 (1997-06-01)
The modifying effects of dimethylarsinic acid (DMA), the major metabolite of ingested arsenicals in most mammals, on chemical carcinogenesis were investigated using rat in vivo models and reviewed here. In a multi-organ bioassay, rats pretreated with 5 carcinogens were administered
Erik J Tokar et al.
Toxicology letters, 209(2), 179-185 (2012-01-11)
Inorganic arsenic, an early life carcinogen in humans and mice, can initiate lesions promotable by other agents in later life. The biomethylation product of arsenic, dimethylarsinic acid (DMA), is a multi-site tumor promoter. Thus, pregnant CD1 mice were given drinking
Hua Naranmandura et al.
Toxicological sciences : an official journal of the Society of Toxicology, 128(1), 137-146 (2012-04-28)
Arsenic is known to be a human carcinogen as well as one of the most effective drugs for treatment of patients with acute promyelocytic leukemia. The intermediate metabolites of arsenic, monomethylarsonous acid (MMA(III)) and dimethylarsinous acid (DMA(III)), are formed by

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