A2252

Adenosine 5′-monophosphate monohydrate

from yeast, ≥97%

• Sinónimos: 5′-AMP, A-5′-P, AMP
• Fórmula empírica (notación de Hill): C₁₀H₁₄N₅O₇P · H₂O
• Número de CAS: 18422-05-4
• Peso molecular: 365.24
• Beilstein: 54612
• Número MDL: MFCD00149360
• Código UNSPSC: 41106305
• eCl@ss: 32160414
• ID de la sustancia en PubChem: 24890637
• NACRES: NA.51

Propiedades

• origen biológico: yeast
• Nivel de calidad: 200
• Ensayo: ≥97%
• Formulario: powder
• solubilidad: 1 M NH4OH: soluble 50 mg/mL, clear, colorless; H₂O: soluble (with addition of mild alkali)
• temp. de almacenamiento: −20°C
• cadena SMILES: O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N)=NC=N3)O[C@@H]1COP(O)(O)=O.O
• InChI: 1S/C10H14N5O7P.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);1H2/t4-,6-,7-,10-;/m1./s1
• Clave InChI: ZOEFQKVADUBYKV-MCDZGGTQSA-N

Descripción

Aplicación

Adenosine 5′-monophosphate (5′AMP) is suitable for use as

• a reagent in the synthesis of adenosine-5′-phosphoimidazolide[1]
• an activator of phosphorylase b in the polymerization reaction for the synthesis of branched polysaccharides[2]
• an inhibitor of endogenous NMN adenylyltransferase (NMNAT) activity that converts NMN to NAD⁺[3]

Acciones bioquímicas o fisiológicas

Adenosine 5′-monophosphate (5′-AMP) has many uses in nature. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). AMP inhibits dephosphorylation of AMPK and promotes phosphorylation of AMPK by upstream kinases.[4]

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable