31404

Dextran sulfate sodium salt from Leuconostoc spp.

M_r 5,000

• Número de CAS: 9011-18-1
• Número MDL: MFCD00081551
• Código UNSPSC: 12161700
• NACRES: NA.21

Propiedades

• origen biológico: (Leuconostoc spp.)
• Nivel de calidad: 200
• Formulario: powder
• mol peso: M_r 5,000
• composición: Sulfur Content, 16.0-20.0%
• pérdida: ≤10% loss on drying
• intervalo de pH útil: 6.0-8.0 (10 g/L)
• solubilidad: H₂O: 0.1 g/mL, clear, colorless to slightly yellow; water: 100 g/L at 25 °C (77 °F ); H₂O: freely soluble 50 mg/mL, clear
• temp. de almacenamiento: room temp

Descripción

Aplicación

Dextran sulfate sodium salt from Leuconostoc sp. is a polyanion used as a test reagent for testing its capability to rupture the extracellular enveloped virus (EEV) outer membrane. It has also been used for assessing the impact of TLR4 monoclonal antibody on the growth of dextran-sulfate-sodium-(DSS)-induced colitis.

Acciones bioquímicas o fisiológicas

Dextran is a mixture of glucose polymers of varying size and geometry.Dextran in the form of dextran sulphate sodium acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength. The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.

Nota de preparación

prepared from dextran with M_r ~5000

Otras notas

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)