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281M-8

Sigma-Aldrich

MART-1 (Melan A) (A103) Mouse Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

A103, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (281M-84)
vial of 0.5 mL concentrate (281M-85)
bottle of 1.0 mL predilute (281M-87)
vial of 1.0 mL concentrate (281M-86)
bottle of 7.0 mL predilute (281M-88)

fabricante / nombre comercial

Cell Marque®

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotipo

IgG1

control

melanoma

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

cytoplasmic

Información sobre el gen

human ... MLANA(2315)

Descripción general

MART-1 (also known as melan A) is a melanoma antigen recognized by T cells.1-2 MART-1 is a transmembrane protein present in melanocytes of normal skin, nevi, and most melanomas. MART-1 is a useful marker for identifying melanomas.

Calidad


IVD

IVD

IVD

RUO

Ligadura / enlace

MART-1 Positive Control Slides, Product No. 281S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: [email protected]

Información legal

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Cynthia Kucher et al.
The American Journal of dermatopathology, 26(6), 452-457 (2004-12-25)
Desmoplastic melanoma (DMM) is an uncommon melanoma variant with a distinct morphology, including a prominent spindle cell component with fibrosis, as well as a distinct immunohistochemical profile. Histologically, the spindle cell component of DMM can be confused with sclerotic/desmoplastic nevi
Ravi Suchak et al.
The American Journal of dermatopathology, 36(5), 387-391 (2014-01-08)
To assess the usefulness of routine melan-A immunohistochemistry (IHC) for exclusion of microinvasion in lentigo maligna (LM). One hundred and twenty cases of LM from our archives were reviewed by 2 authors with S100 protein and melan-A IHC using a
P G Coulie et al.
The Journal of experimental medicine, 180(1), 35-42 (1994-07-01)
It has been reported previously that antitumor cytolytic T lymphocyte (CTL) clones can be isolated from blood lymphocytes of HLA-A2 melanoma patients, after stimulation in vitro with autologous tumor cells, and that some of these CTL clones lyse most HLA-A2
Y Kawakami et al.
Proceedings of the National Academy of Sciences of the United States of America, 91(9), 3515-3519 (1994-04-26)
By cDNA expression cloning we have isolated a gene encoding a shared human melanoma antigen recognized by HLA-A2 restricted autologous and allogenic tumor-infiltrating lymphocytes (TILs) from patients with metastatic melanoma. By using both transient and stable expression systems, transfection of
Z Orosz
Histopathology, 34(6), 517-525 (1999-06-26)
The purpose of this study was to test different malignant non-melanocytic tumours with the commercially available antibody Melan-A to examine its diagnostic specificity and to compare the S100, Melan-A and HMB-45 reactivity in various melanocytic lesions. Seventy-three benign and malignant

Artículos

IHC antibodies enhance dermatopathology beyond H&E stained slides, improving techniques and applications for dermatological research.

IHC antibodies enhance dermatopathology beyond H&E stained slides, improving techniques and applications for dermatological research.

IHC antibodies enhance dermatopathology beyond H&E stained slides, improving techniques and applications for dermatological research.

IHC antibodies enhance dermatopathology beyond H&E stained slides, improving techniques and applications for dermatological research.

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Diagnostic immunohistochemistry overview highlights its importance in cancer diagnosis and detecting infectious diseases in modern clinical pathology.

Diagnostic immunohistochemistry overview highlights its importance in cancer diagnosis and detecting infectious diseases in modern clinical pathology.

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