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104R-1

Sigma-Aldrich

CD4 (SP35) Rabbit Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100
500

conjugado

unconjugated

forma del anticuerpo

culture supernatant

tipo de anticuerpo

primary antibodies

clon

SP35, monoclonal

descripción

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formulario

buffered aqueous solution

reactividad de especies

human

envase

vial of 0.1 mL concentrate (104R-14)
vial of 0.5 mL concentrate (104R-15)
bottle of 1.0 mL predilute (104R-17)
vial of 1.0 mL concentrate (104R-16)
bottle of 7.0 mL predilute (104R-18)

fabricante / nombre comercial

Cell Marque®

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotipo

IgG

control

tonsil

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

visualización

cytoplasmic, membranous

Información sobre el gen

human ... CD4(920)

Descripción general

CD4 is a 55-kD glycoprotein expressed on the surface of T-helper/regulatory T-cells,monocytes, macrophages, and some dendritic cells. The majority of peripheral T-celllymphomas are derived from the T-helper/regulatory cell subset so most matureT-cell neoplasms are CD4+. Anti-CD4 is used to identify normal T-cells and to aid in theidentification of neoplasms of T-cell origin.

Calidad


IVD

IVD

IVD

RUO

Ligadura / enlace

CD4 Positive Control Slides, Product No. 104S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparación

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Otras notas

For Technical Service please contact: 800-665-7284 or email: [email protected]

Información legal

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Cynthia Lehe et al.
Cancer research, 68(15), 6350-6359 (2008-08-05)
Compelling evidences indicate a key role for regulatory T cells (T(reg)) on the host response to cancer. The Wilms' tumor antigen (WT1) is overexpressed in several human leukemias and thus considered as promising target for development of leukemia vaccine. However
Manual of Diagnostic Antibodies for Immunohistology (2003)
Takashi Akiyama et al.
Pathology international, 58(10), 626-634 (2008-09-20)
The present study reports five CD8+, CD56+ (natural killer (NK)-like) T-cell lymphomas involving the small intestine without evidence of enteropathy, from Japan. Three were intestinal T-cell lymphoma. The site of origin of the other two was not definitive. Four of
Adriana Garcia-Herrera et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 26(20), 3364-3371 (2008-06-11)
To define the clinical and pathologic characteristics of primary cutaneous small/medium CD4(+) T-cell lymphoma (PCSM-TCL) and identify parameters of prognostic significance. We have investigated 24 patients with primary cutaneous lymphomas composed of small/medium mature T-cells with a betaF1, CD3, CD4(+)
Atsushi Tanaka et al.
Cell reports, 43(2), 113810-113810 (2024-02-20)
Metastatic progression of colorectal adenocarcinoma (CRC) remains poorly understood and poses significant challenges for treatment. To overcome these challenges, we performed multiomics analyses of primary CRC and liver metastases. Genomic alterations, such as structural variants or copy number alterations, were

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