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Documentos clave

Y0001458

Piretanide for system suitability

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Piretanide, 4-Phenoxy-3-(1-pyrrolidinyl)-5-sulfamoylbenzoic acid

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About This Item

Fórmula empírica (notación de Hill):
C17H18N2O5S
Número de CAS:
55837-27-9
Peso molecular:
362.40
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

piretanide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[S](=O)(=O)(N)c1c(c(cc(c1)C(=O)O)N3CCCC3)Oc2ccccc2

InChI

1S/C17H18N2O5S/c18-25(22,23)15-11-12(17(20)21)10-14(19-8-4-5-9-19)16(15)24-13-6-2-1-3-7-13/h1-3,6-7,10-11H,4-5,8-9H2,(H,20,21)(H2,18,22,23)

InChI key

UJEWTUDSLQGTOA-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Piretanide for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Related product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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R Prestel et al.
Transplant international : official journal of the European Society for Organ Transplantation, 9 Suppl 1, S437-S441 (1996-01-01)
Postischemic kidney function may be influenced by donor conditioning. The sulfamoyl-benzoate "piretanide" (P) is a diuretic agent with an inhibitory effect on the luminal Na-K-2CL-transporter system in the ascending part of the loop of Henle. A clinical pilot study demonstrated
V Homuth et al.
The American journal of cardiology, 72(9), 666-671 (1993-09-15)
To test the dose responses of piretanide, ramipril, and their combination in patients with essential hypertension, a prospective, randomized, double-blind, placebo-controlled trial was conducted in 480 patients. Twelve separate groups were studied: placebo, piretanide 3 mg, piretanide 6 mg, ramipril
N Takamura et al.
Pharmaceutical research, 13(7), 1015-1019 (1996-07-01)
The purpose of this study was to investigate the binding mechanism of loop diuretics with HSA and to characterize the binding site on HSA. Quantitative analysis of potential interaction between ligands bound to HSA was performed by equilibrium dialysis and
Vinicio Granados-Soto et al.
Pain, 114(1-2), 231-238 (2005-03-01)
The possible local peripheral and spinal (intrathecal) antinociceptive effect of Na(+)-K(+)-2Cl(-) cotransporter (NKCC) inhibitors was investigated in the rat formalin test. Nociceptive flinching behavior induced by formalin (1%) injection in the hind paw was assessed following administration of cotransporter inhibitors.
L Thijs et al.
Journal of cardiovascular pharmacology, 26(1), 33-38 (1995-07-01)
In a double-blind, randomized, multicenter trial, we compared the efficacy and safety of the fixed combination of 5 mg ramipril and 6 mg piretanide and the respective component monotherapies in hypertensive patients [supine diastolic blood pressure (DBP) 100-114 mm Hg].
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