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Merck

Y0000196

Ondansetron for TLC system suitability

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Ondansetron hydrochloride dihydrate, 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride, GR 38032F

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About This Item

Fórmula empírica (notación de Hill):
C18H19N3O · HCl · 2H2O
Número de CAS:
Peso molecular:
365.85
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

En este momento no podemos mostrarle ni los precios ni la disponibilidad

grade

pharmaceutical primary standard

API family

ondansetron

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].[H]O[H].[H]O[H].Cc1nccn1CC2CCc3c(C2=O)c4ccccc4n3C

InChI

1S/C18H19N3O.ClH.2H2O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2;;;/h3-6,9-10,13H,7-8,11H2,1-2H3;1H;2*1H2

Inchi Key

VRSLTNZJOUZKLX-UHFFFAOYSA-N

Gene Information

human ... HTR3A(3359)

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Este artículo
P6374SRP2108SRP2107
Sigma-Aldrich

P6249

p53 human

p53 human recombinant, expressed in baculovirus infected Sf21 cells

P6374

p53 human

recombinant

expressed in E. coli

recombinant

expressed in baculovirus infected Sf21 cells

recombinant

expressed in E. coli

recombinant

expressed in E. coli

assay

≥90% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

≥80% (SDS-PAGE)

assay

≥80% (SDS-PAGE)

form

buffered aqueous glycerol solution

form

aqueous solution

form

frozen liquid

form

frozen liquid

UniProt accession no.

P04637

UniProt accession no.

P04637

UniProt accession no.

P04637

UniProt accession no.

P04637

Gene Information

human ... TP53(7157)

Gene Information

human ... TP53(7157)

Gene Information

human ... TP53(7157)

Gene Information

human ... TP53(7157)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ondansetron for TLC system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

5-HT3 serotonin receptor antagonist

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Related product

Referencia del producto
Descripción
Precios

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Daniel Hervás et al.
Pediatric emergency care, 28(11), 1166-1168 (2012-11-02)
In this study, we determine the clinical impact of 1 dose of oral ondansetron for children with vomiting and evaluate the economic consequences of its use. The strategies compared were administering oral ondansetron in addition to oral rehydration therapy (group
Roger M Browning et al.
Regional anesthesia and pain medicine, 38(1), 39-43 (2012-10-30)
Cesarean delivery is commonly performed under regional anesthesia, which is often associated with maternal shivering. This can cause distress and interfere with monitoring. The study objective was to evaluate the antishivering efficacy of ondansetron, which reduces the incidence and severity
João Maria Corrêa Filho et al.
Addictive behaviors, 38(4), 2044-2051 (2013-02-12)
Ondansetron has emerged as a promising medication for the treatment of alcohol dependence, mainly among early-onset alcoholics. This research primarily aimed to evaluate the efficacy and safety of ondansetron at a 16mg/day dosage to treat alcohol-dependent outpatients. A double-blind, placebo-controlled
Hitendra S Mahajan et al.
Carbohydrate polymers, 91(2), 618-625 (2012-11-06)
The objective of present study was to enhance bioadhesive potential of xyloglucan by thiolation. Thiolation of xyloglucan was achieved with esterification with thioglycolic acid. Thiolated xyloglucan was characterized by NMR, DSC, and XRD analysis. Thiolated xyloglucan was determined to possess
Björn Pasternak et al.
The New England journal of medicine, 368(9), 814-823 (2013-03-01)
Ondansetron is frequently used to treat nausea and vomiting during pregnancy, but the safety of this drug for the fetus has not been well studied. We investigated the risk of adverse fetal outcomes associated with ondansetron administered during pregnancy. From

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