SMB00958

N-Desmethyl imatinib

≥95%

• Sinónimos: N-(4-Methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)-4-(piperazin-1-ylmethyl)benzamide, N-Desmethylimatinib, N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-(1-piperazinylmethyl)benzamide, CGP74588, Desmethyl Gleevec, Norimatinib
• Fórmula empírica (notación de Hill): C₂₈H₂₉N₇O
• Número de CAS: 404844-02-6
• Peso molecular: 479.58
• UNSPSC Code: 12352205
• NACRES: NA.77

Propiedades

• biological source: synthetic
• Quality Level: 200
• grade: research grade
• assay: ≥95%
• form: solid
• mol wt: 479.58 g/mol
• storage condition: (Tightly closed. Dry. Keep in a well -ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.)
• technique(s): HPLC: suitable
• solubility: ethanol: 0.20 mg/mL; DMF: 16 mg/mL
• storage temp.: 2-8°C
• InChI: 1S/C28H29N7O/c1-20-4-9-24(17-26(20)34-28-31-12-10-25(33-28)23-3-2-11-30-18-23)32-27(36)22-7-5-21(6-8-22)19-35-15-13-29-14-16-35/h2-12,17-18,29H,13-16,19H2,1H3,(H,32,36)(H,31,33,34)
• Inchi Key: BQQYXPHRXIZMDM-UHFFFAOYSA-N

Descripción

General description

N-Desmethyl imatinib is a pharmacologically active metabolite of imatinib with long elimination half-life. Imatinib is metabolized to N-desmethyl imatinib by CYPs 3A4 and 2C8.

Application

Application: Metabolomics research

Other Notes

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Información de seguridad

• pictograms: GHS08
• signalword: Danger
• hcodes: H341,H351,H360D,H362
• pcodes: P201 - P202 - P260 - P263 - P264 - P308 + P313
• Hazard Classifications: Carc. 2 - Lact. - Muta. 2 - Repr. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable