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Merck

PHR1205

Supelco

Fosfato de tributilo

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

TBP, TBPA

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About This Item

Fórmula lineal:
(CH3(CH2)3O)3PO
Número de CAS:
Peso molecular:
266.31
Beilstein/REAXYS Number:
1710584
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to Ph. Eur. Y0000279

vapor density

9.2 (vs air)

vapor pressure

27 mmHg ( 178 °C)
7.3 mmHg ( 150 °C)

API family

tributyl phosphate

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.424 (lit.)

bp

180-183 °C/22 mmHg (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CCCCOP(=O)(OCCCC)OCCCC

InChI

1S/C12H27O4P/c1-4-7-10-14-17(13,15-11-8-5-2)16-12-9-6-3/h4-12H2,1-3H3

InChI key

STCOOQWBFONSKY-UHFFFAOYSA-N

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General description

Tributyl phosphate is an industrial chemical, commonly used as a plasticizer and a solvent for the extraction of uranium and plutonium in nuclear industry.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Ion Mobility: TWCCSN2 value of 164.9 Å2 [M+H]+ and 182.2 Å2 [M+Na]+

The collision cross section (CCS) measurement was provided by Waters Corporation, using the SYNAPT XS mass spectrometer.
For a description and overview of how ion mobility enables the measurement of the CCS of an ion visit ims.waters.com.
Further information on the SYNAPT XS mass spectrometer can be found on the IMS microsite and product webpage.

TWCCS measurements are expected to be within 2% of this reference value.

P/N PHR1205 is part of the Waters Extractables & Leachables UNIFI scientific library which can be downloaded from Waters Marketplace.

Footnote

To see an example of a Certificate of Analysis for this material enter P500205 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

293.0 °F - closed cup

flash_point_c

145 °C - closed cup


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Improved determination of tributyl phosphate degradation products (mono-and dibutyl phosphates) by ion chromatography
Dodi A and Verda G
Journal of Chromatography A, 920(1-2), 275-281 (2001)
Omar Arous et al.
Journal of hazardous materials, 180(1-3), 493-498 (2010-05-19)
In this work, a development of polymeric inclusion membranes for the cations separation is reported. The membrane was made up of cellulose triacetate (CTA) with a tributyl phosphate (TBP) incorporated into the polymer as metal ions carrier. The transport of
Recep Ali Kumbasar
Journal of hazardous materials, 178(1-3), 875-882 (2010-03-17)
The facilitated extraction of Cr(VI) through an emulsion liquid membrane (ELM) was investigated, using tributyl phosphate (TBP) as mobile carrier. The emulsion liquid membrane phase consists of kerosene as diluent, TBP as carrier, SPAN 80 as surfactant and (NH(4))(2)CO(3) solution
Siu Hua Chang et al.
Journal of hazardous materials, 190(1-3), 197-204 (2011-04-16)
The objectives of this work were to select suitable design parameters and optimize the operating parameters of a soybean oil-based bulk liquid membrane (BLM) for Cu(II) removal and recovery from aqueous solutions. The soybean oil-based BLM consists of an aqueous
C R Deeken et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 96(2), 199-206 (2011-01-07)
Extracellular matrix (ECM) materials are currently utilized for soft tissue repair applications such as vascular grafts, tendon reconstruction, and hernia repair. These materials are derived from tissues such as human dermis and porcine small intestine submucosa, which must be rendered

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