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P3800000

Proxyphylline

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

7-(β-Hydroxypropyl)theophylline, (1,3-Dimethyl-7-[2-hydroxypropyl]-2,6-dioxopurine), Proxyphylline

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About This Item

Fórmula empírica (notación de Hill):
C10H14N4O3
Número de CAS:
603-00-9
Peso molecular:
238.24
MDL number:
MFCD00022833
UNSPSC Code:
41116107
PubChem Substance ID:
329820192
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

proxyphylline

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(O)Cn1cnc2N(C)C(=O)N(C)C(=O)c12

InChI

1S/C10H14N4O3/c1-6(15)4-14-5-11-8-7(14)9(16)13(3)10(17)12(8)2/h5-6,15H,4H2,1-3H3

InChI key

KYHQZNGJUGFTGR-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Proxyphylline EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

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A R Khare et al.
Journal of biomaterials science. Polymer edition, 4(3), 275-289 (1993-01-01)
Controlled release systems of theophylline, proxyphylline and oxprenolol.HCl exhibiting modulated drug delivery were prepared by using pH-sensitive anionic copolymers of 2-hydroxyethyl methacrylate with acrylic acid or methacrylic acid. Drug release studies were carried out in simulated biological fluids. The initial
D Agbaba et al.
Biomedical chromatography : BMC, 6(3), 141-142 (1992-05-01)
The content and dissolution rate of theophylline, diprophylline and proxyphylline from a sustained release formulation were determined by UV in situ densitometry. After separation the chromatographic zones corresponding to the spots of theophylline, diprophylline and proxyphylline on the high performance
M E McNeill et al.
Journal of biomaterials science. Polymer edition, 4(3), 305-322 (1993-01-01)
This study examines the state of water-association with poly(ethylene oxide), as evidenced by diffusivity, in a series of crosslinked polyurethanes made from poly(ethylene glycols) of a range of molecular weights. As a subsidiary underpinning exercise the correlation of diffusivity with
V Ratsimbazafy et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 48(3), 247-252 (1999-12-28)
Mixtures of Gelucires 50/02 and 50/13 showing different hydrophilic-lipophilic balances (HLB) and of proxyphylline were used to prepare suspensions at a concentration of 25% and to manufacture extended release hard gelatin capsules by cooling. The rheological behaviors of Gelucire mixtures
R Duclos et al.
International journal of pharmaceutics, 182(2), 145-154 (1999-05-26)
Three polyol behenates with similar melting points (MP) and different hydrophilic-lipophilic balances (HLB) were studied (MP/HLB: 70/02, 63/05 and 57/13). After melting at MP+30 degrees C, the rheological behaviour of behenates was determined by adjustment of the rheograms to the
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