N6160

Novobiocina sodium salt

meets USP testing specifications

• Sinónimos: Novobiocin sodium salt
• Fórmula empírica (notación de Hill): C₃₁H₃₅N₂NaO₁₁
• Número de CAS: 1476-53-5
• Peso molecular: 634.61
• Beilstein/REAXYS Number: 3892910
• EC Number: 216-023-6
• UNSPSC Code: 51286504
• PubChem Substance ID: 24897774
• NACRES: NA.76

Propiedades

• agency: USP/NF; meets USP testing specifications
• Quality Level: 200
• form: powder
• antibiotic activity spectrum: Gram-positive bacteria
• application(s): pharmaceutical (small molecule)
• mode of action: DNA synthesis | interferes; enzyme | inhibits
• storage temp.: 2-8°C
• SMILES string: [Na+].CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3C([O-])=C(NC(=O)c4ccc(O)c(C\C=C(\C)C)c4)C(=O)Oc3c2C)OC1(C)C
• InChI: 1S/C31H35N2O11.Na/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29;/h7,9-13,23,25-26,29,34,36H,8H2,1-6H3,(H2,32,39)(H,33,37);/q-1;+1
• InChI key: AXOUUAINTJNFRS-UHFFFAOYSA-N

Descripción

General description

Chemical structure: coumarin-glycoside

Application

Para la producción de ADN plasmídico positivamente superenrollado. Inhibidor de la ADN girasa bacteriana y de la ADN topoisomerasa eucariota. Inhibidor de la ADN-polimerasa dependiente de ARN de retrovirus.

Biochem/physiol Actions

Modo de acción: Inhibe la síntesis de ADN mediante la inhibición de la enzima topoisomerasa II.
Espectro antimicrobiano: Bacterias grampositivas.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H317,H319
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves