M8277

Midodrine hydrochloride

analytical standard, for drug analysis

• Sinónimos: (±)-1-(2,5-Dimethoxyphenyl)-2-glycinamidoethanol
• Fórmula empírica (notación de Hill): C₁₂H₁₈N₂O₄ · HCl
• Número de CAS: 3092-17-9
• Peso molecular: 290.74
• MDL number: MFCD00079455
• UNSPSC Code: 41116107
• PubChem Substance ID: 329818055
• NACRES: NA.24

Propiedades

• grade: analytical standard, for drug analysis
• Quality Level: 100
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• format: neat
• SMILES string: Cl.COc1ccc(OC)c(c1)C(O)CNC(=O)CN
• InChI: 1S/C12H18N2O4.ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13;/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16);1H
• InChI key: MGCQZNBCJBRZDT-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

Descripción

General description

Midodrine is a prodrug and a long acting α-adrenergic stimulating agent, and forms an active metabolite, desglymidodrine, which causes an elevation of the systemic blood pressure with the reduction in heart rate.

Application

Midodrine hydrochloride may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations using different chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

α-Adrenergic agonist; vasoconstrictor

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges