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Merck

E1644

Sigma-Aldrich

Ácido etilenodiaminotetraacético disodium salt dihydrate

98.5-101.5%, BioUltra

Sinónimos:

EDTA disodium salt, EDTA-Na2, Edatamil, Edetato disodium salt dihydrate, Etilenodiaminotetraacetato de disodio dihydrate, Sequestrene Na2

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About This Item

Fórmula empírica (notación de Hill):
C10H14N2Na2O8 · 2H2O
Número de CAS:
Peso molecular:
372.24
Beilstein/REAXYS Number:
3900609
EC Number:
UNSPSC Code:
12352107
PubChem Substance ID:
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

product line

BioUltra

assay

98.5-101.5%

form

powder

reaction suitability

reagent type: chelator

impurities

≤0.005% Phosphorus (P)
≤0.05% NH3
≤0.1% Insoluble matter

pH

4.0-6.0 (0.1 M in H2O)

mp

248 °C (dec.) (lit.)

solubility

H2O: 0.1 M, clear, colorless

cation traces

Al: ≤0.001%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

room temp

SMILES string

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

InChI key

OVBJJZOQPCKUOR-UHFFFAOYSA-L

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General description

Ethylenediaminetetraacetic acid (EDTA) is a substituted diamine and a chelator of metal ions. It has anticoagulant and antibacterial activity. EDTA is an inhibitor of metalloprotease. It evades the undesirable effects of ferric, cupric and manganic ions in bleaching. It blocks cellular division, chlorophyll synthesis and algal biomass production.

Application

Quelante de cationes divalentes. Inhibe las enzimas, como las metaloproteasas, que requieren cationes divalentes para ser activas.

pictograms

Health hazardExclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Inhalation - STOT RE 2 Inhalation

target_organs

Respiratory Tract

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction (2013)
Modulation of matrix metalloproteinase activity by EDTA prevents posterior capsular opacification
Hazra S, et al.
Molecular Vision, 18, 1701-1701 (2012)
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Journal of biological methods, 2(3), e23-e23 (2015-10-13)
Over the past two decades, researchers have struggled to efficiently express foreign DNA in primary macrophages, impeding research progress. The applications of lipofection, electroporation, microinjection, and viral-mediated transfer typically result in disruptions in macrophage differentiation and function, low expression levels
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eLife, 7 (2018-01-23)
Age-related hearing loss (ARHL) is the most common sensory deficit in the elderly. The disease has a multifactorial etiology with both environmental and genetic factors involved being largely unknown. SLC7A8/SLC3A2 heterodimer is a neutral amino acid exchanger. Here, we demonstrated
Steven G Chaulk et al.
Nature protocols, 2(5), 1052-1058 (2007-06-05)
This protocol describes a general method for the preparation of RNAs in which the reactivity or hydrogen-bonding properties of the molecule are modified in a photoreversible fashion by use of a caging strategy. A single caged adenosine, modified at the

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